Direct Meds vs Midi Health
In our scoring, Midi Health edges ahead overall (7.0 vs 6.4 out of 10), and Midi Health costs less for compounded semaglutide (about $1,407 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
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Key differences
- Price
- Midi Health $165.90/mo vs Direct Meds $297/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,407 a year less with Midi Health · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Coverage
- Midi Health 50 states (Direct Meds doesn't publish a state list)
- Included
- Direct Meds: medication, clinician visits, shipping; Midi Health: not stated
- Safety
- FDA warning letters on record: Direct Meds 1, Midi Health none
Direct Meds
Affiliate partnerLegitScript Certified
semaglutide
$297
Our score 6.4/10
Midi Health
Affiliate partnerBest for menopause-focused care with GLP-1 as a metabolic adjunct
semaglutide
$165.90
billed every 4 weeks
Our score 7.0/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Direct Meds
Midi Health
Price
Semaglutide / month
$297/mo
Better on this row: $165.90/mo
billed every 4 weeks
Semaglutide / year (modeled)
$3,564
Better on this row: $2,157
13 charges
Tirzepatide / month
$399/mo
Better on this row: $210/mo
billed every 4 weeks
Tirzepatide / year (modeled)
$4,788
Better on this row: $2,730
13 charges
Oral semaglutide / month
$249/mo
Better on this row: $164/mo
billed every 4 weeks
Oral semaglutide / year (modeled)
$2,988
Better on this row: $2,132
13 charges
Oral tirzepatide / month
$299/mo
Better on this row: $209/mo
billed every 4 weeks
Oral tirzepatide / year (modeled)
$3,588
Better on this row: $2,717
13 charges
Coverage
State availability
List not published
50 states
Oral option listed
Yes
Yes
Included in the price
Medication, clinician visits, shipping
Not disclosed
Terms & safety
Price shown
Before intake
Plan quoted after intake; a price is published
Video visit
Not disclosed
Required
Cancel anytime
No
Not disclosed
Minimum commitment
3-month prepay
Not disclosed
Early-cancellation fee
Yes
Not disclosed
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
August 2026
August 2026
Every dose and plan: Direct Meds · Midi Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Direct Meds if…
- All-inclusive pricing covers medication, consultations, supplies, and 1–2 day temperature-controlled shipping
- LegitScript Certified
- Named 503A pharmacy partners: CraftedRx (MO) and ChemistryRx (PA)
What to weigh up
- 1 FDA warning letter on record
- About $1,407 a year more than Midi Health for compounded semaglutide (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
Choose Midi Health if…
- About $1,407 a year less than Direct Meds for compounded semaglutide at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Publishes its full state list (50 states)
- No FDA warning letters on record (Direct Meds has 1)
What to weigh up
- Does not accept Medicare, Medicaid, or Medi-Cal
- GLP-1 is prescribed at clinician discretion within a menopause plan, not guaranteed at intake
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Direct Meds
6.4/10
Midi Health
7.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Direct Meds vs Midi Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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