CoreAge Rx vs Direct Meds
In our scoring, CoreAge Rx edges ahead overall (8.3 vs 6.4 out of 10), and CoreAge Rx costs less for compounded semaglutide (about $2,616 a year less).
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Key differences
- Price
- CoreAge Rx $79/mo vs Direct Meds $297/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $2,616 a year less with CoreAge Rx)
- Coverage
- CoreAge Rx 50 states (Direct Meds doesn't publish a state list)
- Included
- CoreAge Rx: medication, clinician visits, shipping; Direct Meds: medication, clinician visits, shipping
- Safety
- FDA warning letters on record: CoreAge Rx none, Direct Meds 1

CoreAge Rx
Affiliate partnerBest for lowest-price compounded semaglutide and tirzepatide with one flat price at every dose
semaglutide
$79
Our score 8.3/10
Direct Meds
Affiliate partnerAlso prices oral compounded semaglutide and oral compounded tirzepatide
semaglutide
$297
Our score 6.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
CoreAge Rx
Direct Meds
Price
Semaglutide / month
Better on this row: $79/mo
$297/mo
Semaglutide / year (modeled)
Better on this row: $948
$3,564
Tirzepatide / month
Better on this row: $129/mo
$399/mo
Tirzepatide / year (modeled)
Better on this row: $1,548
$4,788
Oral semaglutide / month
Not listed
$249/mo
Oral tirzepatide / month
Not listed
$299/mo
Coverage
State availability
50 states
List not published
Oral option listed
Not listed
Yes
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Better on this row: Yes
No
Minimum commitment
No long-term contracts; one-time purchases and auto-renewing subscriptions are both offered
3-month prepay
Refunds
Full refund of the medication portion if a provider finds you ineligible, minus a non-refundable $50-$100 consultation fee; no refunds once approved or sent to the pharmacy, and all orders become non-refundable 30 days after purchase.
Not disclosed
Early-cancellation fee
Not disclosed
Yes
FDA warning letters
Better on this row: None on record
1 warning letter
Provider facts checked
October 2026
August 2026
Every dose and plan: CoreAge Rx · Direct Meds
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose CoreAge Rx if…
- About $2,616 a year less than Direct Meds for compounded semaglutide at standing prices
- Publishes its full state list (50 states)
- Cancel anytime
What to weigh up
- Trustpilot has suspended its rating for a breach of guidelines after removing a number of fake reviews
- A 'Fall Sale' countdown timer showed nearly the same time left on two separate visits
Choose Direct Meds if…
- Lists oral compounded semaglutide and oral compounded tirzepatide, which CoreAge Rx doesn't price
- All-inclusive pricing covers medication, consultations, supplies, and 1–2 day temperature-controlled shipping
- LegitScript Certified
What to weigh up
- 1 FDA warning letter on record
- About $2,616 a year more than CoreAge Rx for compounded semaglutide
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
CoreAge Rx
8.3/10
Direct Meds
6.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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No insurance needed · vetted by our editors
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Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →CoreAge Rx vs Direct Meds: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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