Direct Meds vs MEDGm
In our scoring, MEDGm edges ahead overall (7.3 vs 6.4 out of 10), and Direct Meds costs less for compounded semaglutide (about $24 a year less).
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Key differences
- Price
- Direct Meds $297/mo vs MEDGm $299/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $24 a year less with Direct Meds)
- Coverage
- MEDGm 50 states + DC (Direct Meds doesn't publish a state list)
- Included
- Direct Meds: medication, clinician visits, shipping; MEDGm: medication, clinician visits, shipping
- Safety
- FDA warning letters on record: Direct Meds 1, MEDGm none
Direct Meds
Affiliate partnerAbout $24 a year less for compounded semaglutide
semaglutide
$297
Our score 6.4/10
MEDGm
Affiliate partnerPublishes its full state list (50 states + DC)
semaglutide
$299
$179 first month
Our score 7.3/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Direct Meds
MEDGm
Price
Semaglutide / month
Better on this row: $297/mo
$299/mo
$179 first month
Semaglutide / year (modeled)
Better on this row: $3,564
$3,588
Tirzepatide / month
$399/mo
$399/mo
$279 first month
Tirzepatide / year (modeled)
$4,788
$4,788
Oral semaglutide / month
Better on this row: $249/mo
$369/mo
$249 first month
Oral semaglutide / year (modeled)
Better on this row: $2,988
$4,428
Oral tirzepatide / month
$299/mo
Not listed
Coverage
State availability
List not published
50 states + DC
Oral option listed
Yes
Yes
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
No
Better on this row: Yes
Minimum commitment
3-month prepay
Monthly plan or a 3-, 6- or 12-month bundle billed upfront for the full term
Refunds
Not disclosed
'The Subscription Service fee is charged upfront for the contracted term you selected and is non-refundable' — the only exception is a documented medical disqualification, refunded for the months that can no longer be delivered
Early-cancellation fee
Yes
Better on this row: None
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
August 2026
September 2026
Every dose and plan: Direct Meds · MEDGm
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Direct Meds if…
- About $24 a year less than MEDGm for compounded semaglutide at standing prices
- Lists oral compounded tirzepatide, which MEDGm doesn't price
- All-inclusive pricing covers medication, consultations, supplies, and 1–2 day temperature-controlled shipping
What to weigh up
- 1 FDA warning letter on record
- No published state list; confirm yours at signup
Choose MEDGm if…
- Publishes its full state list (50 states + DC)
- Cancel anytime; No early-cancellation fee
- No FDA warning letters on record (Direct Meds has 1)
What to weigh up
- About $24 a year more than Direct Meds for compounded semaglutide
- No dose ladder is published — the site never says which milligram strength you start on or how it steps up
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Direct Meds
6.4/10
MEDGm
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Get started →Direct Meds vs MEDGm: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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