Direct Meds vs MEDVi
In our scoring, MEDVi edges ahead overall (7.1 vs 6.4 out of 10), and Direct Meds costs less for compounded semaglutide (about $24 a year less).
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Key differences
- Price
- Direct Meds $297/mo vs MEDVi $299/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $24 a year less with Direct Meds)
- Coverage
- MEDVi 48 states (Direct Meds doesn't publish a state list)
- Included
- Direct Meds: medication, clinician visits, shipping; MEDVi: medication, clinician visits, shipping, coaching
Direct Meds
Affiliate partnerAbout $24 a year less for compounded semaglutide
semaglutide
$297
Our score 6.4/10
MEDVi
Affiliate partnerBest for switching between compounded and brand-name GLP-1 through one provider
semaglutide
$299
$179 first month
Our score 7.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Direct Meds
MEDVi
Price
Semaglutide / month
Better on this row: $297/mo
$299/mo
$179 first month
Semaglutide / year (modeled)
Better on this row: $3,564
$3,588
Oral semaglutide / month
$249/mo
$249/mo
Oral semaglutide / year (modeled)
$2,988
$2,988
Tirzepatide / month
$399/mo
Not listed
Oral tirzepatide / month
$299/mo
Not listed
Coverage
State availability
List not published
48 states
Oral option listed
Yes
Yes
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Lab work
Not disclosed
Not required
Video visit
Not disclosed
Not required
Cancel anytime
No
Not disclosed
Minimum commitment
3-month prepay
Membership
Early-cancellation fee
Yes
Not disclosed
FDA warning letters
1 warning letter
1 warning letter
Provider facts checked
August 2026
August 2026
Every dose and plan: Direct Meds · MEDVi
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Direct Meds if…
- About $24 a year less than MEDVi for compounded semaglutide at standing prices
- Lists compounded tirzepatide and oral compounded tirzepatide, which MEDVi doesn't price
- Semaglutide and tirzepatide available in both injection and sublingual formats
What to weigh up
- 1 FDA warning letter on record
- No published state list; confirm yours at signup
- FDA warning letter (Sept 2025) for marketing compounded GLP-1s as equivalent to FDA-approved drugs
Choose MEDVi if…
- Publishes its full state list (48 states)
- Both compounded and brand-name (Wegovy, Zepbound) GLP-1 options in one platform
- Oral tablet and injectable formats
What to weigh up
- 1 FDA warning letter on record
- About $24 a year more than Direct Meds for compounded semaglutide
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Direct Meds
6.4/10
MEDVi
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $139/mo
Get started →From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Direct Meds vs MEDVi: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.