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CoreAge Rx vs Cost Plus Drugs

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx
VS
Cost Plus Drugs logo

Cost Plus Drugs

7.1
★★★3.6/5

Best for: the cheapest transparent-pricing brand-name Ozempic channel

Visit Cost Plus Drugs

CoreAge Rx and Cost Plus Drugs are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $99/mo versus $279/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Cost Plus Drugs

Ozempic (branded, WAC + 15% + $5 pharmacy fee)Brand-name
$279/mo
semaglutide

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What’s included

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Cost Plus Drugs

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

CoreAge Rx

8.3/10

Overall

Cost Plus Drugs

7.1/10

Value25%

8.5A
vs
B
8.0

Effectiveness25%

8.5A
vs
B
6.5

User Experience15%

8.5A
vs
B
6.5

Trust & Safety15%

7.8A
vs
B
7.5

Accessibility10%

8.0A
vs
B
8.0

Support10%

8.4A
vs
B
6.0

Features & Coverage

FeatureCoreAge RxCost Plus Drugs
Starting Price$99/mo$279/mo
Features6 features5 features
States Available5050
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

About Cost Plus Drugs

Mark Cuban's transparent-pricing online pharmacy. Sells branded Ozempic at the wholesale acquisition cost plus 15% markup plus a flat $5 pharmacy fee — publicly disclosed margin formula. Pharmacy fulfillment only; no telehealth intake. Ships to all 50 states. Distinct from telehealth platforms that route brand-name semaglutide through similar discount channels.

Read our full Cost Plus Drugs review →

Pros & Cons

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Cost Plus Drugs

What we like

  • Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
  • Around $279/mo for branded Ozempic — well below typical retail list prices
  • Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
  • Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
  • Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing

Watch-outs

  • Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
  • Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
  • Wegovy availability has been spotty — check current stock before assuming it ships
  • No compounded semaglutide or tirzepatide — brand only
  • No clinical follow-up — side-effect monitoring falls to your prescribing clinician

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out Cost Plus Drugs with a higher overall score of 8.3/10 and is particularly strong for best overall value. Cost Plus Drugs remains a solid alternative, especially if you're looking for the cheapest transparent-pricing brand-name Ozempic channel.

Choose CoreAge Rx if…

You want best overall value and a starting price around $99/mo.

Choose Cost Plus Drugs if…

You want the cheapest transparent-pricing brand-name Ozempic channel and a starting price around $279/mo.

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8.2

Enhance MD

Lab-monitored compounded GLP-1 with mandatory video visit

7.1

MEDVi

Switching between compounded and brand-name GLP-1 through one provider

8.1

RxSpan MD

Physician-led, pharmacy-transparent compounded GLP-1 with brand-name options

CoreAge Rx vs Cost Plus Drugs: FAQ

CoreAge Rx is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $279/mo for Cost Plus Drugs. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
CoreAge Rx scores higher overall at 8.3/10 versus 7.1/10, and is particularly strong for best overall value. That said, Cost Plus Drugs is a better fit if you want the cheapest transparent-pricing brand-name Ozempic channel.
CoreAge Rx and Cost Plus Drugs both list availability in 50 states.
CoreAge Rx is an affiliate partner (we may earn a commission on sign-ups through our links); Cost Plus Drugs is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, CoreAge Rx is cheaper at $99/mo versus $279/mo at Cost Plus Drugs.

Key terms, explained

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Continue exploring CoreAge Rx and Cost Plus Drugs head-to-heads in the same category.

Or see the full category ranking.

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