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California Trim Clinic vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
California Trim Clinic logo

California Trim Clinic

6.4
★★★☆☆3.2/5

Best for: perimenopausal women wanting GLP-1 microdosing, 100% virtual

Visit California Trim Clinic →
VS
NewSelf logo

NewSelf

8.3
★★★★☆4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf →

California Trim Clinic and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 6.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

California Trim Clinic

Injectable — 3-month commitment requiredcompounded injection
$199/mo
semaglutide
Injectable — 3-month commitment requiredcompounded injection
$299/mo
tirzepatide

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

California Trim Clinic

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Billed separately

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

California Trim Clinic

6.4/10

Overall

NewSelf

8.3/10

Value25%

5.5A
vs
B
9.0

Effectiveness25%

6.5A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.0A
vs
B
8.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.4A
vs
B
7.9

Features & Coverage

FeatureCalifornia Trim ClinicNewSelf
Starting Price$199/mo✓$100/mo
Features✓8 features6 features
States AvailableNot disclosed49
Compounded—✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warnings✓None1 warning

About California Trim Clinic

California Trim Clinic is a Westlake Village CA peptide/longevity clinic offering a 100% virtual, nationwide GLP-1 program via licensed US providers. Specializes in compounded semaglutide and tirzepatide including a Women's Microdosing & Weight Maintenance program targeting perimenopause and menopause-related weight challenges. The $199 initial plan covers doctor consultation, telehealth setup, and onboarding; ongoing 3-month treatment plans include compounded medication and provider check-ins (pricing discussed post-approval).

Read our full California Trim Clinic review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

California Trim Clinic

What we like

  • Women's microdosing program specifically designed for perimenopause/menopause weight management
  • 100% virtual nationwide telehealth; medications shipped discreetly to patients' homes
  • 503A state-licensed compounding pharmacies with patient-specific prescription preparation
  • $199 initial plan covers doctor consultation, telehealth setup, and full onboarding
  • Ongoing 3-month treatment plans include compounded medication and licensed provider check-ins

Watch-outs

  • Ongoing medication pricing not publicly disclosed — revealed only after $199 intake and provider approval
  • No LegitScript certification or any other third-party accreditation visible on the site
  • No physician names or clinical leadership disclosed publicly
  • States served listed as 'nationwide' for telehealth but no state-by-state list published
  • Microdose framing uses sub-clinical doses — potentially lower weight-loss efficacy than standard GLP-1 protocols

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out California Trim Clinic with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. California Trim Clinic remains a solid alternative, especially if you're looking for perimenopausal women wanting GLP-1 microdosing, 100% virtual.

Choose California Trim Clinic if…

You want perimenopausal women wanting GLP-1 microdosing, 100% virtual and a starting price around $199/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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California Trim Clinic vs NewSelf: FAQ

NewSelf is cheaper. Its lowest ongoing monthly cash price is $100/mo, compared with $199/mo for California Trim Clinic. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
NewSelf scores higher overall at 8.3/10 versus 6.4/10, and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. That said, California Trim Clinic is a better fit if you want perimenopausal women wanting GLP-1 microdosing, 100% virtual.
NewSelf lists availability in 49 states, while California Trim Clinic's state list is not publicly listed.
Neither California Trim Clinic nor NewSelf is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, NewSelf is cheaper at $100/mo versus $199/mo at California Trim Clinic.

Key terms, explained

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Continue exploring California Trim Clinic and NewSelf head-to-heads in the same category.

Or see the full category ranking.

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