California Trim Clinic vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
California Trim Clinic
Best for: perimenopausal women wanting GLP-1 microdosing, 100% virtual
Visit California Trim Clinic →
Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →California Trim Clinic and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $199/mo, and Amazon One Medical edges ahead overall (8.5 vs 6.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
California Trim Clinic
Amazon One Medical
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 530+ providers' prices on their own sites and email you when tracked prices move.
What’s included
California Trim Clinic
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Billed separately
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
California Trim Clinic
6.4/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | California Trim Clinic | Amazon One Medical |
|---|---|---|
| Starting Price | $199/mo | ✓$149/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | — | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About California Trim Clinic
California Trim Clinic is a Westlake Village CA peptide/longevity clinic offering a 100% virtual, nationwide GLP-1 program via licensed US providers. Specializes in compounded semaglutide and tirzepatide including a Women's Microdosing & Weight Maintenance program targeting perimenopause and menopause-related weight challenges. The $199 initial plan covers doctor consultation, telehealth setup, and onboarding; ongoing 3-month treatment plans include compounded medication and provider check-ins (pricing discussed post-approval).
Read our full California Trim Clinic review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
California Trim Clinic
What we like
- Women's microdosing program specifically designed for perimenopause/menopause weight management
- 100% virtual nationwide telehealth; medications shipped discreetly to patients' homes
- 503A state-licensed compounding pharmacies with patient-specific prescription preparation
- $199 initial plan covers doctor consultation, telehealth setup, and full onboarding
- Ongoing 3-month treatment plans include compounded medication and licensed provider check-ins
Watch-outs
- Ongoing medication pricing not publicly disclosed — revealed only after $199 intake and provider approval
- No LegitScript certification or any other third-party accreditation visible on the site
- No physician names or clinical leadership disclosed publicly
- States served listed as 'nationwide' for telehealth but no state-by-state list published
- Microdose framing uses sub-clinical doses — potentially lower weight-loss efficacy than standard GLP-1 protocols
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out California Trim Clinic with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. California Trim Clinic remains a solid alternative, especially if you're looking for perimenopausal women wanting GLP-1 microdosing, 100% virtual.
Choose California Trim Clinic if…
You want perimenopausal women wanting GLP-1 microdosing, 100% virtual and a starting price around $199/mo.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Wellorithm
Compounded GLP-1 access with oral tablet options across 49 states
From $147/mo
Get started →AgelessRx
Longevity-focused GLP-1 care
From $139/mo
Get started →Willow
Mainstream telehealth GLP-1 access
From $299/mo
Get started →California Trim Clinic vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring California Trim Clinic and Amazon One Medical head-to-heads in the same category.
- California Trim Clinic vs Vytora Health
- California Trim Clinic vs Collective
- California Trim Clinic vs CoreAge Rx
- Amazon One Medical vs EverSlim
- Amazon One Medical vs Found
- Amazon One Medical vs NewSelf
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.