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Brightmeds vs TMates

In our scoring, Brightmeds edges ahead overall (7.4 vs 6.9 out of 10), and Brightmeds costs less for compounded semaglutide (about $720 a year less).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Brightmeds $189/mo vs TMates $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $720 a year less with Brightmeds)
Coverage
Brightmeds 47 states; TMates 50 states (only TMates: Alabama, Arkansas and Mississippi)
Included
Brightmeds: medication, clinician visits, shipping, labs; TMates: medication, clinician visits, shipping, coaching

How we compare providers

Brightmeds logo

Brightmeds

Affiliate partner

Best for compounded or brand GLP-1 bundled with TRT and peptides for men

semaglutide

$189/mo

Our score 7.4/10

TMates logo

TMates

Affiliate partner

Best for nationwide compounded GLP-1 availability including Puerto Rico

semaglutide

$249/mo

Our score 6.9/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Brightmeds

TMates

Price

Semaglutide / month

Better on this row: $189/mo

$249/mo

Semaglutide / year (modeled)

Better on this row: $2,268

$2,988

Tirzepatide / month

Better on this row: $289/mo

$297/mo

Tirzepatide / year (modeled)

Better on this row: $3,468

$3,564

Coverage

State availability

47 states

50 states

Included in the price

Medication, clinician visits, shipping, labs

Medication, clinician visits, shipping, coaching

Terms & safety

Price shown

Plan quoted after intake; a price is published

Before intake

Cancel anytime

Not disclosed

Yes

Minimum commitment

Not disclosed

None

Refunds

Conditional 6-mo money-back guarantee

Not disclosed

FDA warning letters

None on record

None on record

Provider facts checked

August 2026

August 2026

Show where they differ by state

Only TMates (3 states)

  • Alabama
  • Arkansas
  • Mississippi

Every dose and plan: Brightmeds · TMates

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Brightmeds logo

Choose Brightmeds if…

  • About $720 a year less than TMates for compounded semaglutide at standing prices
  • One login covers GLP-1, TRT, peptides, and longevity — convenient for men exploring weight loss and hormones
  • Offers both compounded GLP-1s and brand-name FDA-approved Zepbound (pens and vials)

What to weigh up

  • Not available in Alabama, Arkansas or Mississippi
  • Pricing isn't itemized on the main pages — you must click through to landers or the application flow
TMates logo

Choose TMates if…

  • Serves Alabama, Arkansas and Mississippi, where Brightmeds doesn't
  • All-inclusive monthly price covers medication, consults, nutrition coaching, and 24/7 support — no separate membership fee
  • Fast stated turnaround — 2–3 days from intake to delivery

What to weigh up

  • About $720 a year more than Brightmeds for compounded semaglutide
  • No third-party pharmacy accreditation (no LegitScript, PCAB, ACHC, or NABP)

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Brightmeds

7.4/10

Overall

TMates

6.9/10

Value25%

6.0A
vs
B
6.5

Effectiveness25%

8.5A
vs
B
7.5

User Experience15%

6.5A
vs
B
8.0

Trust & Safety15%

8.8A
vs
B
5.3

Accessibility10%

8.0A
vs
B
7.5

Support10%

6.5A
vs
B
6.5

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7.2

Willow

Needle-free compounded semaglutide or tirzepatide tablets

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From $299/mo

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7.6

SkinnyRx

Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price

Read full review →

From $149.25/mo

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8.3

Collective

The lowest flat medication price if you can absorb an annual membership fee

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From $59/mo + membership

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Brightmeds vs TMates: FAQ

For compounded semaglutide, Brightmeds costs less: about $720 less a year at the standing price, with no prepay or separate membership listed (not a first-month promo). See Costs & coverage above for each medication side by side.
Brightmeds scores higher overall at 7.4/10 versus 6.9/10, and is particularly strong for compounded or brand GLP-1 bundled with TRT and peptides for men. That said, TMates is a better fit if you want nationwide compounded GLP-1 availability including Puerto Rico.
Both Brightmeds and TMates are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
Brightmeds: $189, about $2,268 a year. TMates: $249, about $2,988 a year. Brightmeds costs about $720 less a year at these prices.
Both serve 47 states. Only TMates serves Alabama, Arkansas and Mississippi.
Brightmeds doesn't state its cancellation terms. TMates: cancel anytime — yes; minimum commitment — None; early-cancellation fee — not disclosed. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Brightmeds and TMates head-to-heads in the same category.

Or see the full category ranking.

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