Amazon One Medical vs Tryozi
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.8 out of 10), and Amazon One Medical costs less for brand-name Wegovy / Ozempic (about $13,001 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
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Key differences
- Price
- Amazon One Medical $199/mo vs Tryozi $1,299/mo for brand-name Wegovy / Ozempic (standing prices, no prepay or separate membership listed · about $13,001 a year less with Amazon One Medical · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Coverage
- Both serve the same 50 states
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); Tryozi: medication, clinician visits, shipping, labs
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
Tryozi
Best for the pharmacy named and a price that does not climb with dose
semaglutide
$79
billed every 4 weeks · sale price
Our score 7.8/10
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Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
Tryozi
Price
Brand Wegovy / Ozempic / month
Better on this row: $199/mo
billed every 4 weeks
$1,299/mo
Brand Wegovy / Ozempic / year (modeled)
Better on this row: $2,587
13 charges
$15,588
Brand Zepbound / Mounjaro / month
Better on this row: $299/mo
billed every 4 weeks
$1,399/mo
Brand Zepbound / Mounjaro / year (modeled)
Better on this row: $3,887
13 charges
$16,788
Semaglutide / month
Not listed
$79/mo
billed every 4 weeks · sale price
Tirzepatide / month
Not listed
$129/mo
billed every 4 weeks
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
50 states
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, clinician visits, shipping, labs
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None on the monthly plan; cancel at least 72 hours before your billing date
Refunds
Not disclosed
No refund on cancellation; full refund if a provider disqualifies you medically
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Every dose and plan: Amazon One Medical · Tryozi
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- About $13,001 a year less than Tryozi for brand-name Wegovy / Ozempic at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Lists brand-name Wegovy pill / Rybelsus and brand-name Foundayo, which Tryozi doesn't price
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
What to weigh up
- Price doesn't include medication and labs
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose Tryozi if…
- Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
- Price includes medication and labs; Amazon One Medical's doesn't
- Names all four of its 503A compounding pharmacies: RedRock, Health Warehouse, Precision Medicine and Triad Rx
What to weigh up
- About $13,001 a year more than Amazon One Medical for brand-name Wegovy / Ozempic (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- No refund if you cancel, unless a provider finds you medically ineligible
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Tryozi
7.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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altRX
Low-cost compounded GLP-1s with brand-name Zepbound, Wegovy and Ozempic as options
Read full review →From $89/mo
Get started →RxSpan MD
Physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
Read full review →From $249/mo
Get started →From $79/mo (sale price)
Get started →Amazon One Medical vs Tryozi: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking, or alternatives to Amazon One Medical and Tryozi.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.