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Amazon One Medical vs TeleDocs360

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical
VS
TeleDocs360 logo

TeleDocs360

6.7
★★★☆☆3.4/5

Best for: Cash-pay patients wanting compounded GLP-1 options with transparent base pricing

Visit TeleDocs360

Amazon One Medical and TeleDocs360 are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $399/mo, and Amazon One Medical edges ahead overall (8.5 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

TeleDocs360

Standard dosingCompounded
$399/mo
semaglutide
Standard dosingCompounded
$399/mo
tirzepatide

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What’s included

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

TeleDocs360

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

TeleDocs360

6.7/10

Value25%

8.5A
vs
B
6.5

Effectiveness25%

8.5A
vs
B
7.0

User Experience15%

8.0A
vs
B
6.5

Trust & Safety15%

8.8A
vs
B
6.8

Accessibility10%

9.5A
vs
B
6.5

Support10%

8.0A
vs
B
6.9

Features & Coverage

FeatureAmazon One MedicalTeleDocs360
Starting Price$149/mo$399/mo
Features6 features8 features
States Available50Not disclosed
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

About TeleDocs360

TeleDocs360 is a cash-pay telehealth service offering compounded GLP-1 weight loss medications, including injectable semaglutide and tirzepatide, oral semaglutide, plus phentermine and NAD+ therapy. Licensed providers review an online intake and prescribe when appropriate, with medication shipped monthly to the patient's home. No insurance is required, and HSA/FSA cards are accepted. Standard dosing programs start at $399 per month, with quarterly options at preferred rates. The site does not publish a state list or individual provider credentials.

Read our full TeleDocs360 review →

Pros & Cons

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

TeleDocs360

What we like

  • Transparent $399/month base pricing for standard dosing
  • Multiple GLP-1 options including injectable and oral semaglutide
  • Cash-pay model with HSA/FSA card acceptance
  • Fast online intake and 24-hour prescription approval
  • Cancel anytime between shipments

Watch-outs

  • Compounded-only; no FDA-approved branded options
  • No published state availability list
  • No individual provider credentials or board certifications shown
  • Higher doses increase cost

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out TeleDocs360 with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. TeleDocs360 remains a solid alternative, especially if you're looking for Cash-pay patients wanting compounded GLP-1 options with transparent base pricing.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

Choose TeleDocs360 if…

You want Cash-pay patients wanting compounded GLP-1 options with transparent base pricing and a starting price around $399/mo.

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Amazon One Medical vs TeleDocs360: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.