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Amazon One Medical vs Science & Co

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery

Visit Amazon One Medical
VS
Science & Co logo

Science & Co

7.4
★★★3.7/5

Best for: the cheapest month-to-month compounded rate, if you accept a contact gate

Visit Science & Co

Amazon One Medical and Science & Co are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Science & Co starts lower at $89/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

Science & Co

Once-weekly compounded injection, month-to-month plan (renews every 30 days)Compounded
$89/mo
semaglutide

Month-to-month rate from the plan table. Prepay tiers: 3-month $250 ($83/mo), 6-month $486 ($81/mo), 12-month $948 ($79/mo) — each billed in one upfront charge.

Once-weekly compounded injection, month-to-month plan (renews every 30 days)Compounded
$139/mo
tirzepatide

Month-to-month rate from the plan table. Prepay tiers: 3-month $399 ($133/mo), 6-month $774 ($129/mo), 12-month $1,500 ($125/mo) — each billed in one upfront charge.

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What’s included

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Science & Co

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

Science & Co

7.4/10

Value25%

8.5A
vs
B
8.5

Effectiveness25%

8.5A
vs
B
8.0

User Experience15%

8.0A
vs
B
6.5

Trust & Safety15%

8.8A
vs
B
5.5

Accessibility10%

9.5A
vs
B
7.5

Support10%

8.0A
vs
B
7.5

Features & Coverage

FeatureAmazon One MedicalScience & Co
Starting Price$149/mo$89/mo
Features6 features6 features
States Available50Not disclosed
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

About Science & Co

Science & Co is a cash-pay telehealth service selling compounded semaglutide from $89/mo and compounded tirzepatide from $139/mo month-to-month, flat at every dose, with free overnight shipping and no membership fee. Those are among the lowest month-to-month GLP-1 rates we track, but the marketing site quotes only '$2 a day' and a 12-month rate buried in a collapsed FAQ; the plan table with the real month-to-month price appears only after you hand over your name, email, phone and state.

Read our full Science & Co review →

Pros & Cons

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Science & Co

What we like

  • $89/mo month-to-month for compounded semaglutide is at the bottom of the range we track
  • Flat at every dose — 'You pay the same whether you are on your starting dose or your highest one'
  • Free overnight shipping, no membership fee and no consultation fee
  • Prepay tiers are cheaper per month and are shown side by side with the monthly rate, not instead of it
  • Published phone line and email, both staffed as 24/7 messaging with the care team
  • HSA and FSA eligible
  • Cancel any time before the next renewal from the patient portal

Watch-outs

  • The marketing site quotes only a per-day figure and the 12-month rate; the plan table appears only after you give your name, email, phone and state
  • Trustpilot has removed this company's profile as against its guidelines, while the site advertises '4.8 · 1,200+ member reviews'
  • The LegitScript badge is a self-hosted image on the company's own CDN, not a LegitScript-served seal, and its lookup shows no record
  • The monthly plan 'renews every 30 days' — 13 charges in a year, not 12
  • The advertised '$79 a month' is the 12-month tier: a single $948 charge up front
  • The compounding pharmacy is never named; the company states it is 'not a 503A or 503B compounding facility'
  • Marketing consent to email and text arrives pre-checked on the contact step
  • Named before/after testimonials repeat across pages, and the '15% lost on average' figure is labeled illustrative

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Science & Co with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Science & Co remains a solid alternative, especially if you're looking for the cheapest month-to-month compounded rate, if you accept a contact gate.

Choose Amazon One Medical if…

You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.

Choose Science & Co if…

You want the cheapest month-to-month compounded rate, if you accept a contact gate and a starting price around $89/mo.

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Amazon One Medical vs Science & Co: FAQ

Science & Co is cheaper. Its lowest ongoing monthly cash price is $89/mo, compared with $149/mo for Amazon One Medical. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Amazon One Medical scores higher overall at 8.5/10 versus 7.4/10, and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. That said, Science & Co is a better fit if you want the cheapest month-to-month compounded rate, if you accept a contact gate.
Amazon One Medical lists availability in 50 states, while Science & Co's state list is not publicly listed.
Neither Amazon One Medical nor Science & Co is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

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