Amazon One Medical vs Rila
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →
Rila
Best for: people who want compounded semaglutide or tirzepatide month to month, with no charge unless prescribed
Visit Rila →Amazon One Medical and Rila are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $249/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
Rila
3, 6 and 12-month plans cost $639, $1,188 and $2,196 ($213, $198 and $183 a month)
3, 6 and 12-month plans cost $705, $1,000 and $2,419.44
3, 6 and 12-month plans cost $849, $1,589 and $2,988 ($283, $265 and $249 a month)
3, 6 and 12-month plans cost $783, $1,456 and $2,694.60
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 530+ providers' prices on their own sites and email you when tracked prices move.
What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Rila
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Rila
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | Rila |
|---|---|---|
| Starting Price | ✓$149/mo | $249/mo |
| Features | 6 features | ✓7 features |
| States Available | 50 | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About Rila
Rila is a Utah telehealth company that sells compounded semaglutide and tirzepatide as weekly injections or dissolving tablets, prescribed through the Dr. TelX medical group and filled by three named pharmacies. Monthly plans cost $249 for semaglutide injections and $349 for tirzepatide injections. The advertised $198 is the monthly average of a 6-month plan, and you are not charged unless a provider prescribes.
Read our full Rila review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Rila
What we like
- You are not charged unless a licensed provider reviews your answers and prescribes treatment
- Offers semaglutide and tirzepatide, each as a weekly injection or a dissolving tablet
- Names its medical group and all three dispensing pharmacies, with addresses, on its site
- Publishes which states get online-only care and which require a live visit first
- A certified medical assistant is assigned to each patient at no extra cost
- Shipping is free and arrives in discreet packaging
- Support is available by phone as well as email, and FSA or HSA cards are accepted
Watch-outs
- The advertised $198 is the monthly average of a 6-month semaglutide plan; month-to-month starts at $249
- The "from $217" tablet price does not match any plan we could find in the checkout data
- Full plan prices appear only after you enter an email address in the intake
- Charges are non-refundable once a billing cycle starts, and you must cancel 72 hours before renewal
- Kansas, Louisiana, Mississippi, New Mexico, Rhode Island, West Virginia and DC require a live consultation first
- The brand is new and has no independent customer reviews yet
Our Verdict
Amazon One Medical edges out Rila with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Rila remains a solid alternative, especially if you're looking for people who want compounded semaglutide or tirzepatide month to month, with no charge unless prescribed.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
Choose Rila if…
You want people who want compounded semaglutide or tirzepatide month to month, with no charge unless prescribed and a starting price around $249/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Willow
Mainstream telehealth GLP-1 access
From $299/mo
Get started →Fella Health
Men's weight loss
From $165/mo
Get started →SkinnyRx
Mainstream telehealth GLP-1 access
From $149.25/mo
Get started →Amazon One Medical vs Rila: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Amazon One Medical and Rila head-to-heads in the same category.
- Amazon One Medical vs Vytora Health
- Amazon One Medical vs Collective
- Amazon One Medical vs CoreAge Rx
- Rila vs EverSlim
- Rila vs Found
- Rila vs NewSelf
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.