10rx vs Yes Clinic
An in-depth comparison of two leading GLP-1 Providers
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Yes Clinic
Best for: flat per-dose pricing, and seeing every price without a quiz or an account
Visit Yes Clinic →10rx and Yes Clinic are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $96.67/mo versus $129/mo, and Yes Clinic edges ahead overall (7.8 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Yes Clinic
$387 for 3 months = $129/mo. 6 months is $699 = $116.50/mo and is labelled "price locked". No single-month plan renders. Flat at every dose.
$447 for 3 months and $894 for 6 months both work out at $149/mo, "price locked". No single-month plan renders. Flat at every dose.
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Yes Clinic
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Yes Clinic
7.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Yes Clinic |
|---|---|---|
| Starting Price | ✓$96.67/mo | $129/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Yes Clinic
Yes Clinic sells compounded semaglutide and tirzepatide at one flat price that does not rise as your dose is titrated up — $129/mo for semaglutide and $149/mo for tirzepatide, with the consultation, shipping and membership all at $0. Every price is published on the product page without a quiz or an account. The trade-off is that the smallest plan is a three-month prepay charged upfront.
Read our full Yes Clinic review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to pin down
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Yes Clinic
What we like
- Flat price at every dose — $129/mo semaglutide, $149/mo tirzepatide, and it does not climb as you titrate
- At $129/mo semaglutide sits only $20 below tirzepatide, so stepping up costs little
- "Every price is on this page. No quiz and no account needed to see it" — no email wall to see cost
- Consultation ($30), shipping and membership are all listed at $0: "the price on the tile is the whole price"
- Full refund if you cancel before the pharmacy dispenses; cancel yourself from your account
- Bilingual site with a working EN/ES toggle
Watch-outs
- Smallest plan is a 3-month prepay — $387 or $447 charged upfront, not a monthly bill
- Their live Terms of Use still contains an unfilled template placeholder: governed by the laws of the State of {GOVERNING_LAW_STATE}
- No pharmacy partner is named despite a "LegitScript Certified" banner in the footer
- No state list published: "Services are not available in all states"
- Product pages served different prices in source HTML than they render, so quote the figure you see on screen
- Support is email-only; no phone number published
Our Verdict
Yes Clinic edges out 10rx with a higher overall score of 7.8/10 and is particularly strong for flat per-dose pricing, and seeing every price without a quiz or an account. 10rx remains a solid alternative, especially if you're looking for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Choose 10rx if…
You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $96.67/mo.
Choose Yes Clinic if…
You want flat per-dose pricing, and seeing every price without a quiz or an account and a starting price around $129/mo.
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Care Bare Rx
LGBTQ+-inclusive compounded GLP-1 telehealth
From $199/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
Get started →MEDVi
Switching between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →10rx vs Yes Clinic: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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