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10rx vs Amazon One Medical

In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
10rx $96.67/mo for compounded semaglutide; Amazon One Medical $199/mo for brand-name Wegovy / Ozempic (different medications, so not compared on price)
Coverage
Amazon One Medical 50 states (10rx doesn't publish a state list)
Included
10rx: medication, clinician visits, shipping; Amazon One Medical: clinician visits, shipping (not included: medication, labs)

How we compare providers

10rx logo

10rx

Best for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

semaglutide

$96.67/mo

Our score 7.1/10

Amazon One Medical logo

Amazon One Medical

Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery

Brand-name Wegovy / Ozempic

$199/mo

billed every 4 weeks

Our score 8.5/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

10rx

Amazon One Medical

Price

Semaglutide / month

$96.67/mo

Not listed

Tirzepatide / month

$149.67/mo

Not listed

Brand Wegovy / Ozempic / month

Not listed

$199/mo

billed every 4 weeks

Brand Zepbound / Mounjaro / month

Not listed

$299/mo

billed every 4 weeks

Brand Wegovy pill / Rybelsus / month

Not listed

$149/mo

Brand Foundayo / month

Not listed

$149/mo

Coverage

State availability

List not published

50 states

Oral option listed

Not listed

Yes

Brand-name access listed

Not listed

Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo

Included in the price

Medication, clinician visits, shipping

Clinician visits, shipping

Not included: medication, labs

Terms & safety

Price shown

Before intake

Before intake

Lab work

Not disclosed

Required

FDA warning letters

None on record

None on record

Provider facts checked

August 2026

October 2026

Every dose and plan: 10rx · Amazon One Medical

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

10rx logo

Choose 10rx if…

  • Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
  • Price includes medication; Amazon One Medical's doesn't
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility

What to weigh up

  • No published state list; confirm yours at signup
  • Doesn't publish its legal operating entity, so accountability is hard to pin down
Amazon One Medical logo

Choose Amazon One Medical if…

  • Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which 10rx doesn't price
  • Publishes its full state list (50 states)
  • Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible

What to weigh up

  • Price doesn't include medication
  • Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

Amazon One Medical

8.5/10

Value25%

8.5A
vs
B
8.5

Effectiveness25%

7.0A
vs
B
8.5

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

5.3A
vs
B
8.8

Accessibility10%

7.5A
vs
B
9.5

Support10%

6.4A
vs
B
8.0

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6.2

Wellorithm

Compounded GLP-1 access with oral tablet options across 49 states

Read full review →

From $247/mo

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7.1

AgelessRx

Longevity-focused GLP-1 care with microdosing and brand-name options

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From $139/mo

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7.2

Willow

Needle-free compounded semaglutide or tirzepatide tablets

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From $299/mo

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10rx vs Amazon One Medical: FAQ

Amazon One Medical scores higher overall at 8.5/10 versus 7.1/10, and is particularly strong for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery. That said, 10rx is a better fit if you want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Neither 10rx nor Amazon One Medical is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
Not at a published price. 10rx lists compounded semaglutide, compounded tirzepatide; Amazon One Medical lists brand-name Foundayo, brand-name Wegovy pill / Rybelsus, brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro.
10rx doesn't publish a state list. Amazon One Medical publishes 50 states. Where a list isn't published, confirm your state during sign-up before paying.
10rx doesn't state its cancellation terms. Amazon One Medical doesn't state its cancellation terms. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring 10rx and Amazon One Medical head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.