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10rx vs Rylo Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★3.6/5

Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS
Rylo Health logo

Rylo Health

7.7
★★★3.9/5

Best for: shoppers who want the pharmacy and medical group named before they buy

Visit Rylo Health

10rx and Rylo Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $149/mo, and Rylo Health edges ahead overall (7.7 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

Rylo Health

Semaglutide, monthly (standard rate)Compounded
$149/mo
semaglutide

Standard rate $149/mo; quarterly $349. A First 20 promotional rate of $100/mo is advertised for the first 20 patients.

Tirzepatide, monthly (standard rate)Compounded
$249/mo
tirzepatide

Standard rate $249/mo; quarterly $499. A First 20 promotional rate of $160/mo is advertised for the first 20 patients.

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Rylo Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

Rylo Health

7.7/10

Value25%

8.5A
vs
B
8.0

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

7.0A
vs
B
7.5

Trust & Safety15%

5.3A
vs
B
7.5

Accessibility10%

7.5A
vs
B
8.5

Support10%

6.4A
vs
B
7.5

Features & Coverage

Feature10rxRylo Health
Starting Price$99.67/mo$149/mo
Features8 features4 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Rylo Health

Texas-prescriber telehealth selling compounded semaglutide and tirzepatide alongside a peptide line, naming both its medical group and its dispensing pharmacy.

Read our full Rylo Health review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Rylo Health

What we like

  • Names its dispensing pharmacy in full, with address and phone: VialsRX in Houston, Texas
  • Names its medical group, Lone Star Virtual Health PLLC, and gives a provider contact
  • Standard prices published openly alongside the promotional rate, so the real ongoing cost is visible
  • Cancel in one click from the patient portal, with no contracts and no cancellation fees
  • Peptide line priced openly, including NAD+ and sermorelin

Watch-outs

  • Headline $100 and $160 rates are limited to the first 20 patients; standard rates are $149 and $249
  • No LegitScript certification is claimed or displayed
  • Several peptide products are advertised as coming soon rather than available
  • No published refund policy beyond the no-cancellation-fee statement

Our Verdict

Winner: Rylo Health

Rylo Health edges out 10rx with a higher overall score of 7.7/10 and is particularly strong for shoppers who want the pharmacy and medical group named before they buy. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.

Choose 10rx if…

You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose Rylo Health if…

You want shoppers who want the pharmacy and medical group named before they buy and a starting price around $149/mo.

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8.1

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Mainstream telehealth GLP-1 access

7.6

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Compounded GLP-1 alongside NAD+, peptide and longevity add-ons

6.2

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Compounded GLP-1 access with oral tablet options across 49 states

10rx vs Rylo Health: FAQ

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