10rx vs One80Rx
An in-depth comparison of two leading GLP-1 Providers
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One80Rx
Best for: low listed GLP-1 prices with flat dosing, including microdose and oral options
Visit One80Rx →10rx and One80Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $96.67/mo versus $129/mo, and 10rx edges ahead overall (7.1 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
One80Rx
Card reads "from $129/mo"; the site says plans are confirmed after provider review.
Card reads "from $229/mo"; the site says plans are confirmed after provider review.
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
One80Rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
One80Rx
6.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | One80Rx |
|---|---|---|
| Starting Price | ✓$96.67/mo | $129/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About One80Rx
One80Rx is a Tampa-based telehealth platform selling compounded semaglutide and tirzepatide injections, plus a GLP-1 microdose program, an oral GLP-1 and a long list of peptides. Listed prices start at $129/mo for semaglutide and $229/mo for tirzepatide, and the site promises flat pricing with no dose-change surcharge. The catch is that every price is a "from" figure confirmed only after provider review, and the brand launched in mid-2026.
Read our full One80Rx review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to pin down
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
One80Rx
What we like
- Low listed entry prices: semaglutide from $129/mo and tirzepatide from $229/mo
- Flat-rate pricing is promised with no consultation fee and no surcharge when your dose goes up
- $0 if a provider does not approve you, and the Terms refund you if no prescription is issued
- Four GLP-1 formats, including a lower-dose microdose program and a daily oral option
- Free 2–3 day shipping in temperature-controlled, unmarked packaging
- Support phone line and email published, with weekday hours of 9 AM to 5 PM
- Cancel from your patient portal by turning off auto-refill at least 48 hours before the next charge
Watch-outs
- Every price is a "from" figure confirmed only after provider review; the treatment pages show no price at all
- No price appears in the intake before it asks for your name, email, phone, birth date and shipping address
- Neither the compounding pharmacy nor the prescribing medical group is named anywhere on the site
- Shows a Trustpilot "4.8 / 5" rating, but no Trustpilot profile for the brand could be found
- Brand launched in mid-2026, yet the homepage claims "10k+" members beside a "1,743+ patients supported" counter
- Terms make you waive the right to fill your prescription at a pharmacy of your choice
- No refunds once medication is dispensed, and order cancellation is limited to 24 hours after purchase
- Compounded semaglutide and tirzepatide are not FDA-approved, as the site itself states
Our Verdict
10rx edges out One80Rx with a higher overall score of 7.1/10 and is particularly strong for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. One80Rx remains a solid alternative, especially if you're looking for low listed GLP-1 prices with flat dosing, including microdose and oral options.
Choose 10rx if…
You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $96.67/mo.
Choose One80Rx if…
You want low listed GLP-1 prices with flat dosing, including microdose and oral options and a starting price around $129/mo.
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Brightmeds
Compounded or brand GLP-1 bundled with TRT and peptides for men
From $100/mo
Get started →Direct Meds
Listed for disclosure only — see its FDA warning and BBB complaints first
From $249/mo
Get started →Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →10rx vs One80Rx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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