10rx vs Aspire Health
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons
Visit 10rx →
Aspire Health
Best for: compounded + brand GLP-1s (Wegovy/Zepbound) with labs included and named PA/NP team in Nebraska telehealth
Visit Aspire Health →10rx and Aspire Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $205/mo, and 10rx edges ahead overall (7.0 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Compounded; GLP-1 options as low as under $100/mo
Compounded GLP-1 + GIP
Aspire Health
Verbatim from weight-loss page: '$149' for 5-week supply of compounded semaglutide/B6 (low dose 0.25–0.5 mg) + $75/month LoseIt program fee = ~$205/month total. 'Medication costs are not included in either program fee.' 15-week supply listed at $399 (~$115/mo for medication alone). program fee enrollment fee $200 ($175 online).
Verbatim from weight-loss page: '$199' for 5-week supply of compounded semaglutide/B6 (high dose 1.7+ mg) + $75/month LoseIt program fee = ~$247/month total. 15-week supply listed at $499 (~$144/mo for medication alone). 'Medication costs are not included in either program fee.'
Verbatim from weight-loss page: '$199' for 4-week supply of Wegovy (brand semaglutide, starter doses) + $75/month LoseIt program fee = ~$274/month total. Other Wegovy doses listed at $399/4 weeks (~$474/mo total with program fee). 'Medication costs are not included in either program fee.'
Verbatim from weight-loss page: '$249' for 5-week supply of compounded tirzepatide/B6 (2.5 mg) + $75/month LoseIt program fee = ~$289/month total. 15-week supply at $699 (~$202/mo for medication alone). 'Medication costs are not included in either program fee.'
Verbatim from weight-loss page: '$349' for 5-week supply of compounded tirzepatide/B6 (5–15 mg) + $75/month LoseIt program fee = ~$375/month total. 15-week supply at $999 (~$289/mo for medication alone). 'Medication costs are not included in either program fee.'
Verbatim from weight-loss page: '$299' for 4-week supply of Zepbound (brand tirzepatide, 2.5 mg) + $75/month LoseIt program fee = ~$374/month total. Higher doses (7.5–15 mg) listed at $449/4wks (~$524/mo total with program fee). 'Medication costs are not included in either program fee.'
What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Aspire Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Included
Coaching
Included
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.0/10
Aspire Health
6.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Aspire Health |
|---|---|---|
| Starting Price | ✓$99.67/mo | $205/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Aspire Health
Aspire Health is a Nebraska-based telehealth practice offering both compounded semaglutide/tirzepatide (formulated with B6) and brand-name Wegovy and Zepbound, prescribed by a named PA/NP clinical team. The LoseIt membership ($200 enrollment + $75/month) includes lab orders with interpretation, provider visits every 2–3 months, Slimpossible app access, and ongoing support — with medication billed separately starting at $149 per 5-week supply for compounded semaglutide.
Read our full Aspire Health review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Aspire Health
What we like
- Both compounded and brand-name options (Wegovy + Zepbound) — rare among GLP-1 telehealth providers
- Lab orders with interpretation included in LoseIt membership — not billed separately
- Named clinical team: founded by Jenni Haan, MPAS, PA-C (18+ years experience) with four additional credentialed providers
- Slimpossible app + secure messaging for ongoing support between provider visits
- HSA/FSA accepted; Cherry third-party financing available for patients needing payment plans
Watch-outs
- Membership fee ($75/month) stacks on top of separately billed medication — total spend $205–$524/month depending on dose
- No LegitScript certification or independent third-party accreditation disclosed
- States served not publicly listed; availability depends on individual provider licensure
- All medication sales are final once shipped; consultation fee non-refundable once completed
- Compounding pharmacy partner not named on any public page
Our Verdict
10rx edges out Aspire Health with a higher overall score of 7.0/10 and is particularly strong for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Aspire Health remains a solid alternative, especially if you're looking for compounded + brand GLP-1s (Wegovy/Zepbound) with labs included and named PA/NP team in Nebraska telehealth.
Choose 10rx if…
You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.
Choose Aspire Health if…
You want compounded + brand GLP-1s (Wegovy/Zepbound) with labs included and named PA/NP team in Nebraska telehealth and a starting price around $205/mo.
Ready to start? Vetted GLP-1 providers
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Bodybuilding Health+
Fitness-brand compounded GLP-1 with hormone and performance programs
From $179/mo
Get started →Gala
Compounded GLP-1/GIP combo therapy on a yearly subscription with free shipping nationwide
From $149/mo
Get started →Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →10rx vs Aspire Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.