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Jyra Health vs Vytora Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Jyra Health logo

Jyra Health

7.7
★★★3.9/5

Best for: very low-cost compounded semaglutide or tirzepatide in any state

Visit Jyra Health
VS
Vytora Health logo

Vytora Health

8.4
★★★★4.2/5

Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states

Visit Vytora Health

Jyra Health and Vytora Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Jyra Health starts lower at $99/mo versus $150/mo, and Vytora Health edges ahead overall (8.4 vs 7.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Jyra Health

StartingCompounded
$99/mo
semaglutide

'Best Value GLP-1'; no membership/hidden fees, no insurance, free express delivery

Starting (limited time)Compounded
$133/mo
tirzepatide

$133/mo flagged 'Limited Time' — verify current price

Vytora Health

All dosesCompounded
$180/mo
semaglutide
3-mo bundle ($450 billed)Compounded
$150/mo
semaglutide
All dosesCompounded
$249/mo
tirzepatide
3-mo bundle ($599 billed)Compounded
$200/mo
tirzepatide
Brand 5/7.5/10/12.5/15 mgBrand-name
$1399/mo
mounjaro
Brand 2.5/5/7.5/10/12.5/15 mgBrand-name
$1399/mo
zepbound

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What’s included

Jyra Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Vytora Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Jyra Health

7.7/10

Overall

Vytora Health

8.4/10

Value25%

8.0A
vs
B
8.0

Effectiveness25%

7.5A
vs
B
8.5

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
9.3

Accessibility10%

8.5A
vs
B
8.5

Support10%

7.4A
vs
B
8.4

Features & Coverage

FeatureJyra HealthVytora Health
Starting Price$99/mo$150/mo
Features8 features8 features
States Available5051
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Jyra Health

Jyra Health is an online weight-loss and longevity telehealth clinic offering compounded GLP-1 — semaglutide from $99/mo and tirzepatide from $133/mo (limited time) — prescribed by board-certified providers in all 50 states, with no insurance, no monthly membership, no hidden fees, and free express delivery. It publishes a full legal suite (Privacy, Terms, HIPAA, Refunds). Compounded medications are not FDA-approved (disclosed); pricing is promotional, the compounding pharmacy is not named, and its LegitScript badge is self-hosted and not independently verified.

Read our full Jyra Health review →

About Vytora Health

Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides. It names its pharmacy partners publicly — Vials Pharmacy and Greenwich Biosciences — and discloses its operating physician group, uncommon transparency for the category. Compounded semaglutide runs $180/mo ($150 on a 3-month bundle) and tirzepatide $249/mo ($200 bundled).

Read our full Vytora Health review →

Pros & Cons

Jyra Health

What we like

  • Among the lowest compounded pricing — semaglutide from $99/mo and tirzepatide from $133/mo, with no membership and no hidden fees
  • Board-certified providers in all 50 states; no insurance required and free express delivery
  • Offers both compounded semaglutide and tirzepatide, plus a longevity track
  • Full legal suite published (Privacy, Terms, HIPAA, Refunds & Cancellations)

Watch-outs

  • The $133/mo tirzepatide price is flagged 'limited time' — verify current pricing before enrolling
  • Compounded medications are not FDA-approved (the site discloses this) — not brand Wegovy, Zepbound, Ozempic, or Mounjaro
  • Displays a self-hosted LegitScript badge but no verifiable seal or listing
  • Compounding pharmacy not named; appears to be a newer, smaller clinic (~300 patients/month)

Vytora Health

What we like

  • All 50 states plus DC, with per-state video-vs-audio compliance disclosed
  • Both compounded and brand-name options on one platform — uncommon
  • LegitScript Approved and HIPAA compliant
  • Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
  • Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
  • Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
  • Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options

Watch-outs

  • Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
  • Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
  • Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
  • Initial consultation cost not shown on the public pricing page
  • Limited per-prescriber state licensure detail

Our Verdict

Winner: Vytora Health

Vytora Health edges out Jyra Health with a higher overall score of 8.4/10 and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. Jyra Health remains a solid alternative, especially if you're looking for very low-cost compounded semaglutide or tirzepatide in any state.

Choose Jyra Health if…

You want very low-cost compounded semaglutide or tirzepatide in any state and a starting price around $99/mo.

Choose Vytora Health if…

You want compounded or brand-name GLP-1 with named pharmacy partners, 50 states and a starting price around $150/mo.

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8.2

Gala

Compounded GLP-1/GIP combo on a yearly plan with free shipping

6.9

TMates

Nationwide compounded GLP-1 availability including Puerto Rico

7.9

Trimi Health

Budget-conscious shoppers

Jyra Health vs Vytora Health: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.