Clume Health vs Vytora Health
An in-depth comparison of two leading GLP-1 Providers
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Clume Health
Best for: readers who want a separately priced microdose track and named dispensing pharmacies
Visit Clume Health →
Vytora Health
Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states
Visit Vytora Health →Clume Health and Vytora Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Vytora Health starts lower at $150/mo versus $219/mo, and Vytora Health edges ahead overall (8.4 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Clume Health
The $186/mo figure is a 52-week prepaid term, not an ongoing monthly rate.
The $186/mo figure is a 52-week prepaid term, not an ongoing monthly rate.
The $200/mo figure requires a 12-week prepaid term.
The $200/mo figure requires a 12-week prepaid term.
Vytora Health
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What’s included
Clume Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Vytora Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Clume Health
7.1/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Clume Health | Vytora Health |
|---|---|---|
| Starting Price | $219/mo | ✓$150/mo |
| Features | 5 features | ✓8 features |
| States Available | Not disclosed | 51 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Clume Health
Clume Health sells compounded semaglutide and tirzepatide in oral and injectable form across three tiers: a full-dose Signature program from $259/mo, a Microdose/Maintain program from $219/mo, and an NAD+ and sermorelin longevity track. Its terms name four dispensing pharmacies outright, which most compounded sellers will not do. Clinical care runs through OpenLoop, and cheaper per-month rates are available only by prepaying a 12- or 52-week term.
Read our full Clume Health review →About Vytora Health
Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides. It names its pharmacy partners publicly — Vials Pharmacy and Greenwich Biosciences — and discloses its operating physician group, uncommon transparency for the category. Compounded semaglutide runs $180/mo ($150 on a 3-month bundle) and tirzepatide $249/mo ($200 bundled).
Read our full Vytora Health review →Pros & Cons
Clume Health
What we like
- Names four dispensing pharmacies in its terms, a level of disclosure most compounded sellers avoid.
- Offers both full-dose and microdose tracks, so maintenance has its own priced program.
- Sells semaglutide and tirzepatide in oral as well as injectable form.
- Lists what the monthly price covers, including consultation, medication and at-home delivery.
- Cancellation is allowed at any time by email or through the patient portal.
Watch-outs
- The homepage advertises "starting at *$199/month" and "*$159/month", but no program is priced at either figure.
- Those asterisks lead to no footnote anywhere on the page.
- The cheapest advertised rates require prepaying a full term — $186/mo means a 52-week commitment.
- Canceling needs 72 hours' notice before the next billing date or you are charged for that cycle.
- No refund is issued for the month in which you cancel, or for any prior month.
- Personalized options appear only after you accept OpenLoop's telehealth consent.
- No LegitScript seal or other verified trust badge appears anywhere on the site.
- Support is email only; no phone number or published hours.
Vytora Health
What we like
- All 50 states plus DC, with per-state video-vs-audio compliance disclosed
- Both compounded and brand-name options on one platform — uncommon
- LegitScript Approved and HIPAA compliant
- Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
- Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
- Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
- Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options
Watch-outs
- Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
- Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
- Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
- Initial consultation cost not shown on the public pricing page
- Limited per-prescriber state licensure detail
Our Verdict
Vytora Health edges out Clume Health with a higher overall score of 8.4/10 and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. Clume Health remains a solid alternative, especially if you're looking for readers who want a separately priced microdose track and named dispensing pharmacies.
Choose Clume Health if…
You want readers who want a separately priced microdose track and named dispensing pharmacies and a starting price around $219/mo.
Choose Vytora Health if…
You want compounded or brand-name GLP-1 with named pharmacy partners, 50 states and a starting price around $150/mo.
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Get started →Clume Health vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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