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Definition

The cardiovascular outcomes trial of dulaglutide (Trulicity) in 9,901 adults with type 2 diabetes. Gerstein and colleagues (Lancet 2019) reported a 12% relative reduction in MACE over a median of 5.4 years — the first GLP-1 trial to enroll a majority primary-prevention population (where most participants had not yet had a CV event).

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Definition curated by Weight Loss Rankings — sourced from FDA labels and peer-reviewed PubMed literature, never AI-generated summaries.

Related terms in trial

• SURMOUNT-5
• SURMOUNT-2
• SURMOUNT-3
• SURPASS-2
• SUSTAIN-6
• PIONEER 6
• STEP-HFpEF
• EXSCEL
• ELIXA
• AMPLITUDE-O
• HARMONY OUTCOMES
• SCALE Diabetes
• STEP 2
• SUMMIT
• SCALE Maintenance

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