SCALE Maintenance
Definition
The phase 3 trial of liraglutide 3.0 mg for maintenance of weight loss after a low-calorie diet run-in. Wadden and colleagues (Int J Obes 2013) reported that liraglutide preserved -6.2% of run-in weight loss at 56 weeks versus placebo -0.2% — established the weight-loss-maintenance use case for daily-injectable GLP-1s.
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Definition curated by Weight Loss Rankings — sourced from FDA labels and peer-reviewed PubMed literature, never AI-generated summaries.
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