ZYP Medical vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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ZYP Medical
Best for: Men in NE, IA, SD, KS, CO, or AZ wanting low-cost compounded GLP-1s with oral option
Visit ZYP Medical →
Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →ZYP Medical and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $150/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
ZYP Medical
Amazon One Medical
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What’s included
ZYP Medical
What the monthly price covers
Medication
Included
Provider visits
Not disclosed
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
ZYP Medical
7.1/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | ZYP Medical | Amazon One Medical |
|---|---|---|
| Starting Price | $150/mo | ✓$149/mo |
| Features | 6 features | 6 features |
| States Available | 6 | ✓50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About ZYP Medical
ZYP Medical is a men's-health-oriented telehealth practice prescribing compounded GLP-1 medications for weight loss across six states. Compounded semaglutide starts at $150/month, injectable tirzepatide at $233/month, and oral tirzepatide at $250/month, with all prices including medication and shipping. An initial one-hour consultation is $50, and there are no membership fees. Care is provided by Joshua Peterson, FNP-C, a board-certified family nurse practitioner. The company discloses that compounded medications are not FDA-approved and recommends FDA-approved brands as first-line treatment.
Read our full ZYP Medical review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
ZYP Medical
What we like
- Transparent flat-rate pricing including medication and shipping with no hidden fees
- Low $50 initial one-hour consultation
- Offers both injectable and oral tirzepatide options
- No membership fees and pricing decreases as treatment progresses
- Care from a board-certified family nurse practitioner
- Discreet 2-day shipping
Watch-outs
- Compounded medications are not FDA-approved
- Available in only six states (NE, IA, SD, KS, CO, AZ)
- Cash-pay only; no insurance noted
- No named compounding pharmacy partner disclosed
- No LegitScript certification shown on site
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out ZYP Medical with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. ZYP Medical remains a solid alternative, especially if you're looking for Men in NE, IA, SD, KS, CO, or AZ wanting low-cost compounded GLP-1s with oral option.
Choose ZYP Medical if…
You want Men in NE, IA, SD, KS, CO, or AZ wanting low-cost compounded GLP-1s with oral option and a starting price around $150/mo.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
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Get started →ZYP Medical vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.