ZYP Medical Review

ZYP Medical: a small regional practice with low compounded GLP-1 pricing

ZYP Medical is a small telehealth and in-person practice based in Gretna, Nebraska, and it has become one of the cheaper places to start a compounded GLP-1. Compounded semaglutide is quoted at $160 a month, below our $179 median for comparable cash-pay programs. If you live in one of the seven states it serves and want to spend as little as possible, ZYP is worth a look. The catch is that it is a lean operation, with one named prescriber, no insurance, no named pharmacy, and refill prices that change with your dose.

How we get the category median: $179 is the middle value of the cheapest ongoing monthly price (not a first-month promo) at each of the 508 GLP-1 providers we track.

How the pricing actually works

ZYP sells starter plans that are paid in full upfront. Semaglutide is $399 for a 10-week starter, which the site quotes as $160 a month, and a 12-week version is also offered. Compounded tirzepatide injections are $450 for a 2-month starter, or $225 a month, and 3-month plans are available, with Affirm financing offered on both drugs.

After the starter, refills scale with your dose, and ZYP's FAQ explains it plainly: "A higher dose uses more of the vial," so each order is priced on how long the supply will last you. Ask what your refill will cost at each dose before you commit.

What keeps the math friendly is the lack of add-ons, since there's no monthly membership fee. Every new plan starts with a free one-hour consult, and the price covers medication, supplies, shipping, and provider follow-ups. One warning: ZYP's homepage still shows older drug prices and paid consult fees. The weight-loss page and the booking page are newer, so trust those numbers instead.

What you pay for, at a glance

• Compounded semaglutide: $399 for a 10-week starter, quoted as $160/month
• Injectable compounded tirzepatide: $450 for a 2-month starter
• Oral tirzepatide dissolving tablets (ODT): $250 for a 30-day supply in 3, 4, or 5 mg
• Oral tirzepatide chewables: $199 for 30 tablets at 3 mg, with your provider setting how often you take them
• A free one-hour first consult, with no membership fee

The oral tirzepatide options set it apart

Most budget compounded providers stick to injections, but ZYP offers two needle-free forms of tirzepatide: a dissolving tablet held under the tongue and a chewable. That matters if you are needle-averse or want a lower-friction way to stay consistent. Pairing that with low entry pricing is the real reason to pick this practice over a bigger competitor. You are trading polish and broad availability for a cheaper, simpler menu.

Who's actually behind your care

Care at ZYP is delivered by Josh Peterson, FNP-C, a board-certified family nurse practitioner. You can text the provider directly, and visits run by video or phone, or in person at the Gretna clinic. Having a single, named prescriber is a point in ZYP's favor, because you know who is signing off on your treatment. The flip side of a one-provider model is capacity, so a solo practice may be slower to reach than a large platform.

Where the trust gaps are: read this part

ZYP earns credit for one disclosure: it states plainly that compounded medications are not FDA-approved. A few trust signals are missing, though. The site names only a "licensed 503A compounding pharmacy," not which one, and it does not display a LegitScript certification either. ZYP has no FDA warning letter on file, which is good, but it's still worth asking which pharmacy fills your prescription before you pay.

The refund terms are also tight, because all sales are final. On prepaid multi-vial plans, the most you can get back is $100, and only if you cancel before a later vial ships. There's no contract, so you can stop anytime, but prepaid money is mostly spent.

Who should choose ZYP, and who should skip it

ZYP is a strong fit if you live in Nebraska, Iowa, South Dakota, Minnesota, Kansas, Colorado, or Arizona. It suits cash-pay patients whose top priority is a low entry cost. It's a bonus if you want an oral tirzepatide option or an in-person visit in the Omaha area. It is a poor fit if you live outside those seven states or need to bill insurance. It also won't suit you if you want a named pharmacy before you pay. Patients who want brand-name Wegovy or Zepbound should look elsewhere, since ZYP's menu is compounded only.

• Choose it: cash-pay, in one of the seven states, chasing a low start price or wanting an oral option
• Skip it: you need insurance, brand-name drugs, nationwide access, refundable prepay, or a disclosed pharmacy

Bottom line

ZYP Medical delivers on what it promises: cheap, no-membership access to compounded GLP-1s. You get two oral tirzepatide options, a free first consult, and a board-certified prescriber you can text. Go in clear-eyed, though: starter plans are paid upfront and final, refill prices move with your dose, and the pharmacy isn't named. For a budget-minded patient in its service area, it's an easy program to try. See our scoring methodology for how we weigh price against trust signals like these.

Worth pricing against SkinnyRx ($149.25/month) and Midi Health ($164/month) before you commit — both sit close to ZYP Medical on cost and formulation.