Tyde Wellness vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Tyde Wellness
Best for: compounded GLP-1 with five named LegitScript-certified pharmacy partners
Visit Tyde Wellness →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Tyde Wellness and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $119/mo, and NewSelf edges ahead overall (8.3 vs 8.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Tyde Wellness
NewSelf
All dosages same price
All dosages same price
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What’s included
Tyde Wellness
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Tyde Wellness
8.0/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Tyde Wellness | NewSelf |
|---|---|---|
| Starting Price | $119/mo | ✓$100/mo |
| Features | ✓8 features | 6 features |
| States Available | ✓50 | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Tyde Wellness
Tyde Wellness is a 50-state compounded-GLP-1 and longevity telehealth platform spanning weight loss, HRT, hair, and peptides. Its standout is supply-chain transparency — five named, LegitScript-certified 503A compounding pharmacy partners — plus a free consultation and a cancel-anytime subscription. Compounded semaglutide starts at $149/mo, tirzepatide at $249/mo, and low-dose naltrexone from $119/mo.
Read our full Tyde Wellness review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Tyde Wellness
What we like
- All 50 states served (full list published)
- Transparent pricing: semaglutide from $149/mo, tirzepatide from $249/mo
- LegitScript Certified with a verification link
- Five named 503A pharmacy partners with addresses: Belmar (CO), Casa (TX), Olympia (FL), Red Rock (UT), Beaker (TX)
- Free consultation; cancel-anytime subscription with no long-term commitment
- Microdose and full-strength options for both GLP-1s
- Single account covers weight loss, HRT, hair, and longevity peptides
Watch-outs
- Compounded semaglutide and tirzepatide are not FDA-approved finished products
- No brand-name GLP-1s (Wegovy, Zepbound, Mounjaro, Ozempic)
- Tirzepatide priced higher than competitors offering $200-$249/mo
- Corporate address and medical director not publicly disclosed
- No NABP .pharmacy seal visible
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Tyde Wellness with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Tyde Wellness remains a solid alternative, especially if you're looking for compounded GLP-1 with five named LegitScript-certified pharmacy partners.
Choose Tyde Wellness if…
You want compounded GLP-1 with five named LegitScript-certified pharmacy partners and a starting price around $119/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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RxSpan MD
Shoppers wanting physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
From $179/mo
Get started →Strut Health
Oral-lozenge compounded GLP-1 access
From $99/mo
Get started →Yucca Health
Mainstream telehealth GLP-1 access
From $146/mo
Get started →Tyde Wellness vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.