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Tyde Wellness vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Tyde Wellness logo

Tyde Wellness

8.0
★★★★4/5

Best for: compounded GLP-1 with five named LegitScript-certified pharmacy partners

Visit Tyde Wellness
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical

Tyde Wellness and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Tyde Wellness starts lower at $119/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 8.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Tyde Wellness

All doses (microdose + full-strength)Compounded
$149/mo
semaglutide
All doses (microdose + full-strength)Compounded
$249/mo
tirzepatide
Oral tablet (low-dose)Compounded
$119/mo
naltrexone

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

Tyde Wellness

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Tyde Wellness

8.0/10

Overall

Amazon One Medical

8.5/10

Value25%

8.0A
vs
B
8.5

Effectiveness25%

8.0A
vs
B
8.5

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

8.3A
vs
B
8.8

Accessibility10%

8.0A
vs
B
9.5

Support10%

7.9A
vs
B
8.0

Features & Coverage

FeatureTyde WellnessAmazon One Medical
Starting Price$119/mo$149/mo
Features8 features6 features
States Available5050
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Tyde Wellness

Tyde Wellness is a 50-state compounded-GLP-1 and longevity telehealth platform spanning weight loss, HRT, hair, and peptides. Its standout is supply-chain transparency — five named, LegitScript-certified 503A compounding pharmacy partners — plus a free consultation and a cancel-anytime subscription. Compounded semaglutide starts at $149/mo, tirzepatide at $249/mo, and low-dose naltrexone from $119/mo.

Read our full Tyde Wellness review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

Tyde Wellness

What we like

  • All 50 states served (full list published)
  • Transparent pricing: semaglutide from $149/mo, tirzepatide from $249/mo
  • LegitScript Certified with a verification link
  • Five named 503A pharmacy partners with addresses: Belmar (CO), Casa (TX), Olympia (FL), Red Rock (UT), Beaker (TX)
  • Free consultation; cancel-anytime subscription with no long-term commitment
  • Microdose and full-strength options for both GLP-1s
  • Single account covers weight loss, HRT, hair, and longevity peptides

Watch-outs

  • Compounded semaglutide and tirzepatide are not FDA-approved finished products
  • No brand-name GLP-1s (Wegovy, Zepbound, Mounjaro, Ozempic)
  • Tirzepatide priced higher than competitors offering $200-$249/mo
  • Corporate address and medical director not publicly disclosed
  • No NABP .pharmacy seal visible

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Tyde Wellness with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Tyde Wellness remains a solid alternative, especially if you're looking for compounded GLP-1 with five named LegitScript-certified pharmacy partners.

Choose Tyde Wellness if…

You want compounded GLP-1 with five named LegitScript-certified pharmacy partners and a starting price around $119/mo.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

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Tyde Wellness vs Amazon One Medical: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.