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Tuyo Health vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Tuyo Health

7.1
★★★3.6/5

Best for: shoppers wanting low-cost compounded glp-1 on an all-inclusive plan

Visit Tuyo Health
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Tuyo Health and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $155/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Tuyo Health

All doses (flat)Compounded
$155/mo
semaglutide

All-inclusive: protocol, consults, shipping and periodic labs

All doses (flat)Compounded
$279/mo
tirzepatide

All-inclusive compounded plan; brand Zepbound also offered separately

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Tuyo Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Tuyo Health

7.1/10

Overall

NewSelf

8.3/10

Value25%

7.5A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
8.3

Accessibility10%

6.0A
vs
B
8.5

Support10%

7.0A
vs
B
7.9

Features & Coverage

FeatureTuyo HealthNewSelf
Starting Price$155/mo$100/mo
Features6 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Tuyo Health

Tuyo Health (tuyohealth.com) is a US telehealth weight-loss program founded by Dr. German Echeverry that offers both compounded and brand-name GLP-1 medication. Compounded semaglutide starts at 155 dollars per month and compounded tirzepatide at 279 dollars per month, all-inclusive with custom protocol, free same-week shipping, complimentary medical consultations and periodic lab work. Brand-name Wegovy and Zepbound plans start around 399 to 499 dollars per month plus a 99 dollar membership, and can be lower with insurance. Support is by phone at 866-642-8054 and email.

Read our full Tuyo Health review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Tuyo Health

What we like

  • Low starting price of 155 dollars per month for compounded semaglutide, all-inclusive
  • Offers both compounded and brand-name Wegovy and Zepbound, with an insurance option
  • Free same-week shipping, complimentary consults and periodic lab work included

Watch-outs

  • Service-area states not published
  • No specific compounding pharmacy named on the site
  • Brand-name plans add a separate 99 dollar membership fee

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Tuyo Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Tuyo Health remains a solid alternative, especially if you're looking for shoppers wanting low-cost compounded glp-1 on an all-inclusive plan.

Choose Tuyo Health if…

You want shoppers wanting low-cost compounded glp-1 on an all-inclusive plan and a starting price around $155/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Telos Rx

Needle-free and microdosed compounded GLP-1 options with lab-monitored care

6.4

Direct Meds

Listed for transparent disclosure — see FDA warning and BBB complaint pattern before considering

Tuyo Health vs NewSelf: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.