Tuyo Health vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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Tuyo Health
Best for: shoppers wanting low-cost compounded glp-1 on an all-inclusive plan
Visit Tuyo Health →
Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →Tuyo Health and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $155/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Tuyo Health
All-inclusive: protocol, consults, shipping and periodic labs
All-inclusive compounded plan; brand Zepbound also offered separately
Amazon One Medical
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What’s included
Tuyo Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Tuyo Health
7.1/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Tuyo Health | Amazon One Medical |
|---|---|---|
| Starting Price | $155/mo | ✓$149/mo |
| Features | 6 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | 1 warning | ✓None |
About Tuyo Health
Tuyo Health (tuyohealth.com) is a US telehealth weight-loss program founded by Dr. German Echeverry that offers both compounded and brand-name GLP-1 medication. Compounded semaglutide starts at 155 dollars per month and compounded tirzepatide at 279 dollars per month, all-inclusive with custom protocol, free same-week shipping, complimentary medical consultations and periodic lab work. Brand-name Wegovy and Zepbound plans start around 399 to 499 dollars per month plus a 99 dollar membership, and can be lower with insurance. Support is by phone at 866-642-8054 and email.
Read our full Tuyo Health review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
Tuyo Health
What we like
- Low starting price of 155 dollars per month for compounded semaglutide, all-inclusive
- Offers both compounded and brand-name Wegovy and Zepbound, with an insurance option
- Free same-week shipping, complimentary consults and periodic lab work included
Watch-outs
- Service-area states not published
- No specific compounding pharmacy named on the site
- Brand-name plans add a separate 99 dollar membership fee
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out Tuyo Health with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Tuyo Health remains a solid alternative, especially if you're looking for shoppers wanting low-cost compounded glp-1 on an all-inclusive plan.
Choose Tuyo Health if…
You want shoppers wanting low-cost compounded glp-1 on an all-inclusive plan and a starting price around $155/mo.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
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Get started →Tuyo Health vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.