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TrimRx vs Willow

In our scoring, TrimRx edges ahead overall (7.7 vs 7.2 out of 10), and TrimRx costs less for compounded semaglutide (about $1,440 a year less).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
TrimRx $179/mo vs Willow $299/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,440 a year less with TrimRx)
Coverage
Willow 36 states (TrimRx doesn't publish a state list)
Included
TrimRx: medication, clinician visits, shipping; Willow: medication, clinician visits, shipping

How we compare providers

TrimRx logo

TrimRx

Affiliate partner

Best for best overall value

semaglutide

$179/mo

$149 first month

Our score 7.7/10

Willow logo

Willow

Affiliate partner

Best for needle-free compounded semaglutide or tirzepatide tablets

semaglutide

$299/mo

Our score 7.2/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

TrimRx

Willow

Price

Semaglutide / month

Better on this row: $179/mo

$149 first month

$299/mo

Semaglutide / year (modeled)

Better on this row: $2,148

$3,588

Tirzepatide / month

Better on this row: $259/mo

$399/mo

Tirzepatide / year (modeled)

Better on this row: $3,108

$4,788

Oral semaglutide / month

Not listed

$299/mo

Oral tirzepatide / month

Not listed

$399/mo

Brand Wegovy / Ozempic / month

$1,579/mo

Not listed

Brand Zepbound / Mounjaro / month

$1,249/mo

Not listed

Coverage

State availability

List not published

36 states

Oral option listed

Not listed

Yes

Brand-name access listed

Wegovy / Ozempic, Zepbound / Mounjaro

Not listed

Included in the price

Medication, clinician visits, shipping

Medication, clinician visits, shipping

FSA/HSA accepted

Not listed

Yes

Terms & safety

Price shown

Before intake

Before intake

Cancel anytime

Not disclosed

Yes

Minimum commitment

Not disclosed

Monthly auto-renewing plan; no minimum term stated. 'Your program renews automatically so you never miss a dose.'

Refunds

Not disclosed

'If you cancel before your prescription is sent to the pharmacy, you'll receive a full refund within 5-10 business days.' Terms: 'charges are non-refundable once incurred' and prescription products 'are not returnable'.

FDA warning letters

None on record

None on record

Provider facts checked

August 2026

October 2026

Every dose and plan: TrimRx · Willow

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

TrimRx logo

Choose TrimRx if…

  • About $1,440 a year less than Willow for compounded semaglutide at standing prices
  • Lists brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which Willow doesn't price
  • Free shipping with medication delivered to your door monthly — can start as soon as the next day

What to weigh up

  • No published state list; confirm yours at signup
  • Async, questionnaire-based intake — no mandatory video visit with a clinician before prescribing
Willow logo

Choose Willow if…

  • Lists oral compounded semaglutide and oral compounded tirzepatide, which TrimRx doesn't price
  • Publishes its full state list (36 states)
  • Accepts FSA/HSA cards

What to weigh up

  • About $1,440 a year more than TrimRx for compounded semaglutide
  • Pricier than many compounded programs: $299/mo for semaglutide and $399/mo for tirzepatide

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

TrimRx

7.7/10

Overall

Willow

7.2/10

Value25%

8.0A
vs
B
7.0

Effectiveness25%

8.5A
vs
B
7.5

User Experience15%

7.5A
vs
B
7.0

Trust & Safety15%

6.8A
vs
B
7.3

Accessibility10%

7.0A
vs
B
7.5

Support10%

7.5A
vs
B
7.0

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7.6

SkinnyRx

Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price

Read full review →

From $149.25/mo

Get started →
8.3

Collective

The lowest flat medication price if you can absorb an annual membership fee

Read full review →

From $59/mo + membership

Get started →
7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

Read full review →

From $219/mo

Get started →

TrimRx vs Willow: FAQ

For compounded semaglutide, TrimRx costs less: about $1,440 less a year at the standing price, with no prepay or separate membership listed (not a first-month promo). See Costs & coverage above for each medication side by side.
TrimRx scores higher overall at 7.7/10 versus 7.2/10, and is particularly strong for best overall value. That said, Willow is a better fit if you want needle-free compounded semaglutide or tirzepatide tablets.
Both TrimRx and Willow are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
TrimRx: $179, about $2,148 a year; first month $149. Willow: $299, about $3,588 a year. TrimRx costs about $1,440 less a year at these prices.
TrimRx doesn't publish a state list. Willow publishes 36 states. Where a list isn't published, confirm your state during sign-up before paying.
TrimRx doesn't state its cancellation terms. Willow: cancel anytime — yes; minimum commitment — Monthly auto-renewing plan; no minimum term stated. 'Your program renews automatically so you never miss a dose.'; early-cancellation fee — not disclosed. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring TrimRx and Willow head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.