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TelePeptide vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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TelePeptide logo

TelePeptide

8.2
★★★★4.1

Best for: All-in compounded GLP-1 (sema/tirz, injectable + oral) from $169/mo; LegitScript-certified, 48 states

Visit TelePeptide
VS
Amazon One Medical logo

Amazon One Medical

8.7
★★★★4.4

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical

TelePeptide and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $169/mo, and Amazon One Medical edges ahead overall (8.7 vs 8.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

TelePeptide

Starting doseCompounded
$169/mo
semaglutide

Verbatim from pricing page: Semaglutide Injectable $169/mo (annual prepay), $179/mo (6-month), $199/mo (monthly). All-inclusive — physician eval + Rx + medication + shipping.

Starting doseCompounded
$214/mo
tirzepatide

Verbatim from pricing page: Tirzepatide Injectable $214/mo (annual prepay), $224/mo (6-month), $249/mo (monthly). All-inclusive — physician eval + Rx + medication + shipping.

Starting dose (oral)Compounded
$199/mo
semaglutide

Verbatim from pricing page: Semaglutide Dissolvable Tablet $199/mo (annual prepay), $209/mo (6-month), $229/mo (monthly). Oral sublingual formulation; all-inclusive.

Starting dose (oral)Compounded
$219/mo
tirzepatide

Verbatim from pricing page: Tirzepatide Dissolvable Tablet $219/mo (annual prepay), $229/mo (6-month), $249/mo (monthly). Oral sublingual formulation; all-inclusive.

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

What’s included

TelePeptide

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

TelePeptide

8.2/10

Overall

Amazon One Medical

8.7/10

Value25%

8.5A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

8.0A
vs
B
9.0

Trust & Safety15%

8.5A
vs
B
9.0

Accessibility10%

9.0A
vs
B
9.5

Support10%

8.5A
vs
B
8.0

Features & Coverage

FeatureTelePeptideAmazon One Medical
Starting Price$169/mo$149/mo
Features8 features6 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About TelePeptide

TelePeptide is a LegitScript-certified US direct-pay telehealth practice offering physician-supervised compounded GLP-1 therapy — semaglutide and tirzepatide — in injectable and oral dissolvable tablet formulations across 48 states and DC (excluding Alaska and Mississippi). Every all-inclusive plan covers the physician evaluation, prescription, medication, and shipping from a 503A-licensed compounding pharmacy, with no insurance required and no hidden fees. The practice is operated under MD Integrations, P.C.

Read our full TelePeptide review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

TelePeptide

What we like

  • LegitScript-certified (seal ID 49966407); 503A-licensed compounding pharmacies
  • All-inclusive from $169/mo annual — physician eval + Rx + medication + shipping, no hidden fees
  • Broadest formulation menu: injectable sema/tirz, oral dissolvable tablets, sema+naltrexone, microdose combos
  • 24/7 care team messaging + regular check-ins + dosage adjustments included at every tier
  • 48 states + DC coverage (excludes only AK + MS); no insurance required; cancel anytime

Watch-outs

  • Compounded medications are not FDA-approved; no pharmacy partner named publicly
  • Monthly billing costs more — $199/mo (monthly) vs $169/mo (annual) for semaglutide injectable; best rate requires annual prepay
  • Labs not included in any plan
  • Founder disclosed by first name only (Ahmed); no physician names or clinical leadership disclosed publicly
  • Tirzepatide injectable at $249/mo (monthly billing) is above the compounded market average

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out TelePeptide with a higher overall score of 8.7/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. TelePeptide remains a solid alternative, especially if you're looking for All-in compounded GLP-1 (sema/tirz, injectable + oral) from $169/mo; LegitScript-certified, 48 states.

Choose TelePeptide if…

You want All-in compounded GLP-1 (sema/tirz, injectable + oral) from $169/mo; LegitScript-certified, 48 states and a starting price around $169/mo.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

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TelePeptide vs Amazon One Medical: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.