StackMD vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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StackMD
Best for: shoppers who want an exact price for their specific dose before committing
Visit StackMD →
Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →StackMD and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, StackMD starts lower at $125/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
StackMD
Published per-dose ladder on /product/semaglutide-compounded-glp-1: 1mg $125, 2mg $149, 4mg $175, 6mg $199, 10mg $225 — all 1ml vials of semaglutide with B12 and glycine, billed as a monthly plan ('Plans starting at just $125/month'). No membership or platform fee on top.
Published per-dose ladder on /product/tirzepatide-compounded-glp-1-gip: 5mg $199, 10mg $249, 15mg $299, 20mg $349, 25mg $399, 30mg $449 — all 2ml vials of tirzepatide with B12 and glycine. A patient titrated to a high dose pays more than double the advertised starting price.
Amazon One Medical
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What’s included
StackMD
What the monthly price covers
Medication
Included
Provider visits
Not disclosed
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
StackMD
7.5/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | StackMD | Amazon One Medical |
|---|---|---|
| Starting Price | ✓$125/mo | $149/mo |
| Features | ✓8 features | 6 features |
| States Available | 50 | 50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
About StackMD
StackMD is a New York telehealth platform (Medical 360 HC PLLC) selling compounded semaglutide and tirzepatide, both formulated with B12 and glycine, alongside NAD+, sermorelin and other longevity peptides. It prices every dose strength openly instead of quoting one 'from' number: semaglutide runs $125 to $225 a month across five strengths and tirzepatide $199 to $449 across six. There are no membership fees, and prescribing is handled by its named partner SamaritanMD.
Read our full StackMD review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
StackMD
What we like
- Publishes an exact price for every dose strength rather than a single 'from' figure — semaglutide $125-$225, tirzepatide $199-$449
- Names both its legal entity (Medical 360 HC PLLC) and its prescribing telehealth partner, SamaritanMD
- No membership or platform fee — the medication price is the whole price
- States plainly that its compounded medications are 'not FDA-approved and have not been evaluated by the FDA for safety, efficacy, or quality'
- Telehealth offered in all 50 states per its terms, with free discreet shipping and FSA/HSA eligibility
- Discloses the full formulation, including the B12 and glycine compounded into both GLP-1s
Watch-outs
- All sales are final — 'No refunds are issued except as described below', and dispensed medication cannot be returned
- Compounding pharmacies are never named, only 'a licensed third-party pharmacy'
- Price rises steeply with dose: tirzepatide runs $199 at 5mg to $449 at 30mg
- Billing and refunds are handled by SamaritanMD — StackMD 'has no authority to issue refunds' on its behalf
- Terms impose binding arbitration in New York and waive jury trial and class-action participation
- Both GLP-1s are compounded with added B12 and glycine rather than the single active ingredient
- Availability of specific treatments may still vary by state despite the all-50-states claim
- No LegitScript certification or pharmacy accreditation displayed
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out StackMD with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. StackMD remains a solid alternative, especially if you're looking for shoppers who want an exact price for their specific dose before committing.
Choose StackMD if…
You want shoppers who want an exact price for their specific dose before committing and a starting price around $125/mo.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
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Direct Meds
Listed for transparent disclosure — see FDA warning and BBB complaint pattern before considering
From $249/mo
Get started →Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →StackMD vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.