Silhouette MD vs Vytora Health
In our scoring, Vytora Health edges ahead overall (8.4 vs 7.2 out of 10).
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Key differences
- Price
- Silhouette MD $149/mo no prepay listed; Vytora Health $179/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
- Coverage
- Vytora Health 50 states + DC (Silhouette MD doesn't publish a state list)
- Included
- Silhouette MD: medication, clinician visits (not included: coaching); Vytora Health: medication, clinician visits, shipping
Silhouette MD
Best for hands-on concierge support alongside compounded GLP-1 treatment
semaglutide
$149
“starting at” price
Our score 7.2/10
Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Silhouette MD
Vytora Health
Price
Semaglutide / month
$149/mo
“starting at” price
$179/mo
Semaglutide / year (modeled)
$1,788
$2,148
Tirzepatide / month
$299/mo
“starting at” price
$249/mo
Tirzepatide / year (modeled)
$3,588
$2,988
Oral semaglutide / month
$263/mo
Not listed
Oral tirzepatide / month
$325/mo
Not listed
Brand Zepbound / Mounjaro / month
Not listed
$1,399/mo
Coverage
State availability
List not published
50 states + DC
Oral option listed
Yes
Not listed
Brand-name access listed
Not listed
Zepbound / Mounjaro
Included in the price
Medication, clinician visits
Not included: coaching
Medication, clinician visits, shipping
Terms & safety
Price shown
Plan quoted after intake; a price is published
Before intake
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None on monthly plans; 3-month plans are billed every 3 months
Refunds
Not disclosed
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
October 2026
Every dose and plan: Silhouette MD · Vytora Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Silhouette MD if…
- Lists oral compounded semaglutide and oral compounded tirzepatide, which Vytora Health doesn't price
- Concierge-level support (monitoring, expert guidance, and check-ins) included on every plan
- Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health
What to weigh up
- No published state list; confirm yours at signup
- Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
Choose Vytora Health if…
- Lists brand-name Zepbound / Mounjaro, which Silhouette MD doesn't price
- Publishes its full state list (50 states + DC)
- Both compounded and brand-name options on one platform
What to weigh up
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
- Compounded tirzepatide at $249/mo month-to-month is mid-market
Silhouette MD and Vytora Health in context
Silhouette MD and Vytora Health both list compounded semaglutide, yet the figures are not like-for-like: one figure is a “starting at” price. We leave the cheaper-side call out rather than guess. For a like-for-like field, see the cheapest compounded semaglutide ranking. On score, Silhouette MD is at 7.2 and Vytora Health at 8.4 out of 10.
Only Silhouette MD lists a pill (oral compounded semaglutide). If avoiding injections is the point, read oral vs injectable GLP-1s before choosing on price. Vytora Health publishes where it ships (50 states + DC); Silhouette MD does not publish a state list, so confirm yours at intake or start from providers by state. Vytora Health has LegitScript certification on file and Silhouette MD does not, a point we weigh under trust in the Vytora Health review.
The next head-to-head for Silhouette MD is Silhouette MD vs Amazon One Medical; Amazon One Medical sells orforglipron and semaglutide and lists 50 states. For Vytora Health, it is Vytora Health vs Sipra; Sipra sells semaglutide and tirzepatide. If neither fits, the wider shortlists are alternatives to Silhouette MD and alternatives to Vytora Health.
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Silhouette MD
7.2/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Oak
Compounded semaglutide and tirzepatide at a low starting price, with a full price list before you sign up
Read full review →From $200/mo (starting dose)
Get started →From $99/mo
Get started →From $139/mo (4-month plan rate)
Get started →Silhouette MD vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
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- Silhouette MD vs Amazon One Medical
- Vytora Health vs Amazon One Medical
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- Vytora Health vs Collective
Or see the full category ranking, or alternatives to Silhouette MD and Vytora Health.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.