Amazon One Medical vs Sesame Care
Our featured pick: Sesame Care (affiliate partner). In our scoring, Amazon One Medical scores 8.5 and Sesame Care 8.0 out of 10, and Amazon One Medical costs less for brand-name Wegovy / Ozempic (about $1,601 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
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Key differences
- Price
- Amazon One Medical $199/mo vs Sesame Care $349/mo for brand-name Wegovy / Ozempic (standing prices, no prepay or separate membership listed · about $1,601 a year less with Amazon One Medical · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Coverage
- Amazon One Medical 50 states (Sesame Care doesn't publish a state list)
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); Sesame Care: not stated
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10

Sesame Care
Affiliate partnerBest for Brand-name GLP-1s at cash prices, no compounding
Brand-name Wegovy / Ozempic
$349
$199 first month
Our score 8.0/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
Sesame Care
Price
Brand Wegovy / Ozempic / month
Better on this row: $199/mo
billed every 4 weeks
$349/mo
$199 first month
Brand Wegovy / Ozempic / year (modeled)
Better on this row: $2,587
13 charges
$4,188
Brand Zepbound / Mounjaro / month
$299/mo
billed every 4 weeks
Better on this row: $299/mo
Brand Zepbound / Mounjaro / year (modeled)
$3,887
13 charges
Better on this row: $3,588
Brand Wegovy pill / Rybelsus / month
$149/mo
$149/mo
Brand Wegovy pill / Rybelsus / year (modeled)
$1,788
$1,788
Brand Foundayo / month
$149/mo
$149/mo
Brand Foundayo / year (modeled)
$1,788
$1,788
Coverage
State availability
50 states
List not published
Oral option listed
Yes
Yes
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Included in the price
Clinician visits, shipping
Not included: medication, labs
Not disclosed
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Video visit
Not disclosed
Required
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None
Early-cancellation fee
Not disclosed
None
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
Every dose and plan: Amazon One Medical · Sesame Care
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- About $1,601 a year less than Sesame Care for brand-name Wegovy / Ozempic at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Publishes its full state list (50 states)
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
What to weigh up
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
- You must provide recent lab results (kidney function and glucose or A1c), bought separately if you have none

Choose Sesame Care if…
- Marketplace transparency — pick a named provider with a displayed price before booking, unlike most opaque telehealth intake
- BBB-accredited and LegitScript-certified
- Honest subscription scope — clinical care only, medication billed separately
What to weigh up
- About $1,601 a year more than Amazon One Medical for brand-name Wegovy / Ozempic (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- No published state list; confirm yours at signup
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Sesame Care
8.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Ro
FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help
Read full review →From $149/mo + membership
Get started →ShedRx
Compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans
Read full review →From $149/mo + membership
Get started →From $139/mo
Get started →Amazon One Medical vs Sesame Care: FAQ
Key terms, explained
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.