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Amazon One Medical vs Sesame Care

Our featured pick: Sesame Care (affiliate partner). In our scoring, Amazon One Medical scores 8.5 and Sesame Care 8.0 out of 10, and Amazon One Medical costs less for brand-name Wegovy / Ozempic (about $1,601 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Amazon One Medical $199/mo vs Sesame Care $349/mo for brand-name Wegovy / Ozempic (standing prices, no prepay or separate membership listed · about $1,601 a year less with Amazon One Medical · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
Coverage
Amazon One Medical 50 states (Sesame Care doesn't publish a state list)
Included
Amazon One Medical: clinician visits, shipping (not included: medication, labs); Sesame Care: not stated

How we compare providers

Amazon One Medical logo

Amazon One Medical

Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery

Brand-name Wegovy / Ozempic

$199/mo

billed every 4 weeks

Our score 8.5/10

Sesame Care logo

Sesame Care

Affiliate partner

Best for Brand-name GLP-1s at cash prices, no compounding

Brand-name Wegovy / Ozempic

$349/mo

$199 first month

Our score 8.0/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Amazon One Medical

Sesame Care

Price

Brand Wegovy / Ozempic / month

Better on this row: $199/mo

billed every 4 weeks

$349/mo

$199 first month

Brand Wegovy / Ozempic / year (modeled)

Better on this row: $2,587

13 charges

$4,188

Brand Zepbound / Mounjaro / month

$299/mo

billed every 4 weeks

Better on this row: $299/mo

Brand Zepbound / Mounjaro / year (modeled)

$3,887

13 charges

Better on this row: $3,588

Brand Wegovy pill / Rybelsus / month

$149/mo

$149/mo

Brand Wegovy pill / Rybelsus / year (modeled)

$1,788

$1,788

Brand Foundayo / month

$149/mo

$149/mo

Brand Foundayo / year (modeled)

$1,788

$1,788

Coverage

State availability

50 states

List not published

Oral option listed

Yes

Yes

Brand-name access listed

Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo

Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo

Included in the price

Clinician visits, shipping

Not included: medication, labs

Not disclosed

Terms & safety

Price shown

Before intake

Before intake

Lab work

Required

Not disclosed

Video visit

Not disclosed

Required

Cancel anytime

Not disclosed

Yes

Minimum commitment

Not disclosed

None

Early-cancellation fee

Not disclosed

None

FDA warning letters

None on record

None on record

Provider facts checked

October 2026

August 2026

Every dose and plan: Amazon One Medical · Sesame Care

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Amazon One Medical logo

Choose Amazon One Medical if…

  • About $1,601 a year less than Sesame Care for brand-name Wegovy / Ozempic at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
  • Publishes its full state list (50 states)
  • Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible

What to weigh up

  • Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
  • You must provide recent lab results (kidney function and glucose or A1c), bought separately if you have none
Sesame Care logo

Choose Sesame Care if…

  • Marketplace transparency — pick a named provider with a displayed price before booking, unlike most opaque telehealth intake
  • BBB-accredited and LegitScript-certified
  • Honest subscription scope — clinical care only, medication billed separately

What to weigh up

  • About $1,601 a year more than Amazon One Medical for brand-name Wegovy / Ozempic (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
  • No published state list; confirm yours at signup

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

Sesame Care

8.0/10

Value25%

8.5A
vs
B
7.5

Effectiveness25%

8.5A
vs
B
9.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

8.8A
vs
B
8.0

Accessibility10%

9.5A
vs
B
6.5

Support10%

8.0A
vs
B
8.0

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FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help

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Compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans

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Longevity-focused GLP-1 care with microdosing and brand-name options

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Amazon One Medical vs Sesame Care: FAQ

For brand-name Wegovy / Ozempic, Amazon One Medical costs less: about $1,601 less a year at the standing price, with no prepay or separate membership listed (not a first-month promo); one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost. See Costs & coverage above for each medication side by side.
Our featured pick is Sesame Care, our affiliate partner. Partner status affects which provider we feature, never the scores: on our six-dimension score, Amazon One Medical is 8.5/10 and Sesame Care 8.0/10, so check the key differences and the breakdown above before you choose.
Sesame Care is an affiliate partner (we may earn a commission on sign-ups through our links); Amazon One Medical is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
Amazon One Medical: $199 (billed every 4 weeks, 13 charges a year), about $2,587 a year. Sesame Care: $349, about $4,188 a year; first month $199. Amazon One Medical costs about $1,601 less a year at these prices.
Amazon One Medical publishes 50 states. Sesame Care doesn't publish a state list. Where a list isn't published, confirm your state during sign-up before paying.
Amazon One Medical doesn't state its cancellation terms. Sesame Care: cancel anytime — yes; minimum commitment — None; early-cancellation fee — none. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Amazon One Medical and Sesame Care head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.