RxSpan MD vs CoreAge Rx
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
RxSpan MD
Best for shoppers wanting physician-led, pharmacy-transparent compounded GLP-1 with brand-name optionsStarting at $249/mo
CoreAge Rx
Best for best overall valueStarting at $149/mo
Side-by-Side Comparison
| Feature | RxSpan MD | CoreAge Rx |
|---|---|---|
| Overall Score | 7.4/10 | ✓9.0/10 |
| Starting Price | $249/mo | ✓$149/mo |
| Editorial Rating | 3.7 ★ /5 | ✓4.5 ★ /5 |
| Features | ✓7 features | 6 features |
| States Available | 50 | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
RxSpan MD
What we like
- Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
- Compounded semaglutide and tirzepatide from $249/mo (injection or oral capsules), plus brand-name Wegovy, Zepbound and Ozempic
- Names its 503A pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma) and medical group
- LegitScript-certified (#50405601); free expedited shipping and unlimited 24/7 support included
- Available in all 50 states via a 2-minute assessment
Watch-outs
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
- Brand-name GLP-1 is priced steeply (Wegovy $1,349, Ozempic $1,299, Zepbound $1,069)
- Multi-vertical practice (also hair, sexual health, longevity), not weight-loss-only
- Legal entity name isn't published on the site
CoreAge Rx
What we like
- LegitScript certified — rigorous pharmacy standards
- Free 2-day shipping nationwide
- Both semaglutide and tirzepatide available
- Lowest per-month pricing in the compounded segment
- 24/7 support team
- All 50 states covered
Watch-outs
- Compounded only — no brand-name Ozempic or Wegovy
- Newer brand with fewer independent reviews than legacy players
Our Verdict
CoreAge Rx edges out RxSpan MD with a higher overall score of 9.0/10 and is particularly strong for best overall value. RxSpan MD remains a solid alternative, especially if you're looking for shoppers wanting physician-led, pharmacy-transparent compounded GLP-1 with brand-name options.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring RxSpan MD and CoreAge Rx head-to-heads in the same category.
- RxSpan MD vs TrimRx
- RxSpan MD vs Amazon One Medical
- RxSpan MD vs NovoCare Pharmacy
- CoreAge Rx vs Vytora Health
- CoreAge Rx vs Enhance MD
- CoreAge Rx vs Noom Med
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.