RxPros vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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RxPros
Best for lowest annual-prepay compounded GLP-1 monthly rateStarting at $99.99/mo
Amazon One Medical
Best for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savingsStarting at $25/mo
Side-by-Side Comparison
| Feature | RxPros | Amazon One Medical |
|---|---|---|
| Overall Score | 7.6/10 | ✓8.7/10 |
| Starting Price | $99.99/mo | ✓$25/mo |
| Editorial Rating | 3.8 ★ /5 | ✓4.4 ★ /5 |
| Features | 6 features | 6 features |
| States Available | 0 | ✓50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
RxPros
Pros
- ✓$99.99/month compounded semaglutide — among the cheapest in the US compounded telehealth market
- ✓$144.97/month compounded tirzepatide — at the lower end of the compounded tirzepatide range
- ✓LegitScript Certified
- ✓Named legal entity (RxPros LLC) with a physical Wyoming address
- ✓Overnight cold-packed shipping disclosed — important for GLP-1 cold-chain integrity
- ✓Add-on Zofran (anti-nausea) and B12 available for managing GI side effects during titration
Cons
- ✗Headline pricing requires annual prepay or is introductory — monthly and quarterly rates not clearly shown
- ✗Per-state availability not listed — verify your state ships before committing
- ✗Specific 503A pharmacy partners not named
- ✗Lab work not included as standard
- ✗LegitScript certification number not displayed (seal only)
Amazon One Medical
Pros
- ✓As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- ✓Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- ✓In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- ✓Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- ✓Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- ✓Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Cons
- ✗Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- ✗Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- ✗Pricing is set by manufacturer savings programs and can change at any time
- ✗No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- ✗Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- ✗Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out RxPros with a higher overall score of 8.7/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. RxPros remains a solid alternative, especially if you're looking for lowest annual-prepay compounded GLP-1 monthly rate.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.