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Ro vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Ro logo

Ro

7.7
★★★★☆3.9/5

Best for: broadest GLP-1 formulary including Foundayo on day-one of launch

Visit Ro →
VS
NewSelf logo

NewSelf

8.3
★★★★☆4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf →

Ro and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $149/mo, and Ro is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Ro

Foundayo (lowest dose, cash pay)Brand-name
$149/mo
orforglipron

Additional membership fees apply

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Ro

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Not disclosed

Lab work

Included

Coaching

Included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Ro

7.7/10

Overall

NewSelf

8.3/10

Value25%

6.0A
vs
B
9.0

Effectiveness25%

9.0A
vs
B
8.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.8A
vs
B
8.3

Accessibility10%

7.5A
vs
B
8.5

Support10%

8.5A
vs
B
7.9

Features & Coverage

FeatureRoNewSelf
Starting Price$149/mo✓$100/mo
Features✓7 features6 features
States AvailableNot disclosed49
Compounded—✓ Yes
Brand Name✓ Yes—
FSA/HSA Accepted——
FDA Warnings✓None1 warning

About Ro

Ro is one of the largest direct-to-patient telehealth companies in the US and operates the most comprehensive obesity care formulary in the category — compounded semaglutide, brand-name Wegovy and Zepbound, and as of April 9 2026, Eli Lilly's new oral GLP-1 Foundayo (orforglipron) starting at $149/month for the lowest dose plus membership.

Read our full Ro review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Ro

What we like

  • One of the broadest GLP-1 menus: compounded semaglutide, brand Wegovy, brand Zepbound, and oral Foundayo (orforglipron)
  • Among the first telehealth platforms to offer oral Foundayo at launch (April 2026)
  • A licensed provider helps you pick the best GLP-1 based on cost, insurance, and your health goals
  • Nationwide delivery, including 99% of primary-care deserts
  • Both cash-pay and insurance-eligible options on one platform

Watch-outs

  • Foundayo requires a recurring membership on top of the $149/mo drug price, so total cost runs higher
  • Foundayo pricing above the lowest dose isn't shown until intake
  • State availability and pharmacy partners aren't listed publicly — confirmed at signup
  • Membership and medication are billed separately, which can make the true monthly cost confusing

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: Ro

Ro is our recommended choice here, particularly for broadest GLP-1 formulary including Foundayo on day-one of launch. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose Ro if…

You want broadest GLP-1 formulary including Foundayo on day-one of launch and a starting price around $149/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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7.4

Brightmeds

Compounded or brand GLP-1 bundled with TRT and peptides for men

6.4

Direct Meds

Listed for disclosure only — see its FDA warning and BBB complaints first

7.6

Maximus

Men seeking compounded GLP-1 alongside testosterone optimization

Ro vs NewSelf: FAQ

NewSelf is cheaper. Its lowest ongoing monthly cash price is $100/mo, compared with $149/mo for Ro. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
For most people we'd start with Ro, especially if you want broadest GLP-1 formulary including Foundayo on day-one of launch. NewSelf is a strong alternative and may suit you better for lowest-cost compounded GLP-1 with pharmacy quality transparency — weigh the six-dimension breakdown above to decide which fits your priorities.
NewSelf lists availability in 49 states, while Ro's state list is not publicly listed.
Ro is an affiliate partner (we may earn a commission on sign-ups through our links); NewSelf is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.

Key terms, explained

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Continue exploring Ro and NewSelf head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.