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Ro vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Ro logo

Ro

7.7
★★★3.9/5

Best for: broadest GLP-1 formulary including Foundayo on day-one of launch

Visit Ro
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical

Ro and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, both start around $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Ro

Foundayo (lowest dose, cash pay)Brand-name
$149/mo
orforglipron

Additional membership fees apply

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

Ro

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Not disclosed

Lab work

Included

Coaching

Included

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Ro

7.7/10

Overall

Amazon One Medical

8.5/10

Value25%

6.0A
vs
B
8.5

Effectiveness25%

9.0A
vs
B
8.5

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.8A
vs
B
8.8

Accessibility10%

7.5A
vs
B
9.5

Support10%

8.5A
vs
B
8.0

Features & Coverage

FeatureRoAmazon One Medical
Starting Price$149/mo$149/mo
Features7 features6 features
States AvailableNot disclosed50
Compounded
Brand Name✓ Yes✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Ro

Ro is one of the largest direct-to-patient telehealth companies in the US and operates the most comprehensive obesity care formulary in the category — compounded semaglutide, brand-name Wegovy and Zepbound, and as of April 9 2026, Eli Lilly's new oral GLP-1 Foundayo (orforglipron) starting at $149/month for the lowest dose plus membership.

Read our full Ro review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

Ro

What we like

  • One of the broadest GLP-1 menus: compounded semaglutide, brand Wegovy, brand Zepbound, and oral Foundayo (orforglipron)
  • Among the first telehealth platforms to offer oral Foundayo at launch (April 2026)
  • A licensed provider helps you pick the best GLP-1 based on cost, insurance, and your health goals
  • Nationwide delivery, including 99% of primary-care deserts
  • Both cash-pay and insurance-eligible options on one platform

Watch-outs

  • Foundayo requires a recurring membership on top of the $149/mo drug price, so total cost runs higher
  • Foundayo pricing above the lowest dose isn't shown until intake
  • State availability and pharmacy partners aren't listed publicly — confirmed at signup
  • Membership and medication are billed separately, which can make the true monthly cost confusing

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Ro with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Ro remains a solid alternative, especially if you're looking for broadest GLP-1 formulary including Foundayo on day-one of launch.

Choose Ro if…

You want broadest GLP-1 formulary including Foundayo on day-one of launch and a starting price around $149/mo.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

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Ro vs Amazon One Medical: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.