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Renlo Health vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Renlo Health logo

Renlo Health

7.8
★★★3.9/5

Best for: flat dose pricing with the pharmacy and medical group named

Visit Renlo Health
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery

Visit Amazon One Medical

Renlo Health and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $199/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Renlo Health

Once-weekly compounded injection, billed monthly (flat at every dose)Compounded
$199/mo
semaglutide

'$199/mo' against a struck-through '$299'; '$199 Starting dose / $199 Mid dose / $199 Higher dose'.

Once-weekly compounded injection, billed monthly (flat at every dose)Compounded
$269/mo
tirzepatide

'$269/mo' against a struck-through '$399'; 'Your price stays flat', '$0 increase, at every dose'.

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

Renlo Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Renlo Health

7.8/10

Overall

Amazon One Medical

8.5/10

Value25%

7.5A
vs
B
8.5

Effectiveness25%

8.0A
vs
B
8.5

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.8A
vs
B
8.8

Accessibility10%

8.5A
vs
B
9.5

Support10%

7.0A
vs
B
8.0

Features & Coverage

FeatureRenlo HealthAmazon One Medical
Starting Price$199/mo$149/mo
Features7 features6 features
States Available5050
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Renlo Health

Renlo Health is a telehealth platform selling compounded semaglutide at $199/mo and compounded tirzepatide at $269/mo, flat at every dose, with medication, injection supplies, provider care and expedited shipping in one monthly price and no membership fee. It names both its prescribing medical group and its dispensing pharmacy, and adds NAD+ and glutathione injections as separate longevity products.

Read our full Renlo Health review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

Renlo Health

What we like

  • Flat pricing published before intake: semaglutide $199/mo, tirzepatide $269/mo, same price at every dose
  • Names its prescribing medical group (Arora Health & Aesthetics, LLC, Seattle) and its dispensing pharmacy (VialsRx, Houston)
  • Two named physicians front the clinical side, both identified by name and role
  • One price covers medication, injection supplies, provider evaluation, ongoing care and expedited shipping
  • No membership or consultation fee, and 'Cancel anytime, no fee'
  • LegitScript seal is served from LegitScript's own CDN, not self-hosted
  • You are only charged if a provider prescribes; not approved means a full refund

Watch-outs

  • Tirzepatide at $269/mo sits well above the compounded market's cheaper end
  • The four-month money-back guarantee is narrow — two timed weight verifications, unbroken enrollment, full adherence, and under 2% lost
  • Outside that guarantee 'all sales are final' — no returns on prescription products
  • No phone number is published; support is email only, despite a '24/7 concierge support' claim
  • The intake asks for your mobile number and opts you into SMS before it will go further
  • The all-50-states claim comes with a caveat that medications and fulfillment vary by state
  • Compounded semaglutide and tirzepatide are not FDA-approved

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Renlo Health with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Renlo Health remains a solid alternative, especially if you're looking for flat dose pricing with the pharmacy and medical group named.

Choose Renlo Health if…

You want flat dose pricing with the pharmacy and medical group named and a starting price around $199/mo.

Choose Amazon One Medical if…

You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.

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7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

8.3

Found

Mainstream telehealth GLP-1 access

7.1

Bodybuilding Health+

Fitness-brand compounded GLP-1 with hormone and performance programs

Renlo Health vs Amazon One Medical: FAQ

Amazon One Medical is cheaper. Its lowest ongoing monthly cash price is $149/mo, compared with $199/mo for Renlo Health. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Amazon One Medical scores higher overall at 8.5/10 versus 7.8/10, and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. That said, Renlo Health is a better fit if you want flat dose pricing with the pharmacy and medical group named.
Renlo Health and Amazon One Medical both list availability in 50 states.
Neither Renlo Health nor Amazon One Medical is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

Key terms, explained

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Continue exploring Renlo Health and Amazon One Medical head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.