PlexusDx vs Wellorithm
In our scoring, PlexusDx edges ahead overall (7.0 vs 6.2 out of 10).
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Key differences
- Price
- PlexusDx $129/mo for compounded semaglutide; Wellorithm $247/mo for compounded semaglutide (pill or injection) (different medications, so not compared on price)
- Coverage
- PlexusDx 50 states; Wellorithm 49 states (only PlexusDx: Louisiana)
- Included
- PlexusDx: medication, clinician visits; Wellorithm: not stated
PlexusDx
Affiliate partnerBest for nationwide compounded GLP-1 with optional genetic-test personalization
semaglutide
$129
microdose plan
Our score 7.0/10

Wellorithm
Affiliate partnerBest for compounded GLP-1 access with oral tablet options across 49 states
semaglutide (pill or injection)
$247
$147 first month
Our score 6.2/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
PlexusDx
Wellorithm
Price
Semaglutide / month
$129/mo
microdose plan
Not listed
Tirzepatide / month
$249/mo
starting dose
Not listed
Semaglutide (pill or injection) / month
Not listed
$247/mo
$147 first month
Tirzepatide (pill or injection) / month
Not listed
$347/mo
$247 first month
Coverage
State availability
50 states
49 states
Included in the price
Medication, clinician visits
Not disclosed
Terms & safety
Price shown
Before intake
Plan quoted after intake; a price is published
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Show where they differ by stateHide state lists
Only PlexusDx (1 state)
- Louisiana
Every dose and plan: PlexusDx · Wellorithm
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose PlexusDx if…
- Lists compounded semaglutide and compounded tirzepatide, which Wellorithm doesn't price
- Serves Louisiana, where Wellorithm doesn't
- Optional Precision Peptide genetic panel adds a personalization angle
What to weigh up
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named

Choose Wellorithm if…
- Lists compounded semaglutide (pill or injection) and compounded tirzepatide (pill or injection), which PlexusDx doesn't price
- Four compounded GLP-1 formats: semaglutide and tirzepatide as injectables or oral dissolving tablets
- Available in 49 states — broader than most compounded GLP-1 providers
What to weigh up
- Not available in Louisiana
- Pricing not shown until you complete the intake quiz
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
PlexusDx
7.0/10
Wellorithm
6.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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altRX
Low-cost compounded GLP-1s with brand-name Zepbound, Wegovy and Ozempic as options
Read full review →From $89/mo
Get started →RxSpan MD
Physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
Read full review →From $249/mo
Get started →Luvo Health
Compounded and brand GLP-1s, oral tablets and microdosing on one public price list
Read full review →From $209/4 wks (billed per 4 weeks)
Get started →PlexusDx vs Wellorithm: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking, or alternatives to PlexusDx and Wellorithm.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.