PlexusDx vs YourEra
In our scoring, PlexusDx edges ahead overall (7.0 vs 6.9 out of 10).
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Key differences
- Price
- PlexusDx $129/mo no prepay listed; YourEra $179/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
- Coverage
- PlexusDx 50 states (YourEra doesn't publish a state list)
- Included
- PlexusDx: medication, clinician visits; YourEra: not stated
PlexusDx
Affiliate partnerBest for nationwide compounded GLP-1 with optional genetic-test personalization
semaglutide
$129
microdose plan
Our score 7.0/10
YourEra
Affiliate partnerBest for $99 first-month entry pricing on compounded GLP-1s
semaglutide
$179
$149 first month · starting dose
Our score 6.9/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
PlexusDx
YourEra
Price
Semaglutide / month
$129/mo
microdose plan
$179/mo
$149 first month · starting dose
Semaglutide / year (modeled)
$1,548
$2,148
Tirzepatide / month
$249/mo
starting dose
$259/mo
$179 first month · starting dose
Tirzepatide / year (modeled)
$2,988
$3,108
Coverage
State availability
50 states
List not published
Included in the price
Medication, clinician visits
Not disclosed
Terms & safety
Price shown
Before intake
Before intake
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose PlexusDx if…
- Publishes its full state list (50 states)
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
What to weigh up
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
Choose YourEra if…
- LegitScript Certified
- Clearly states it's 100% online doctor visits and prescriptions
- Honest that the compounded medications aren't brand-name Ozempic, Wegovy, Mounjaro, or Zepbound
What to weigh up
- No published state list; confirm yours at signup
- Ongoing maintenance-dose price isn't published — ask before committing
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
PlexusDx
7.0/10
YourEra
6.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
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RxSpan MD
Physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
Read full review →From $249/mo
Get started →Luvo Health
Compounded and brand GLP-1s, oral tablets and microdosing on one public price list
Read full review →From $209/4 wks (billed per 4 weeks)
Get started →From $99/mo (“starting at” price)
Get started →PlexusDx vs YourEra: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking, or alternatives to PlexusDx and YourEra.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.