PlexusDx vs SkinnyRx
In our scoring, SkinnyRx edges ahead overall (7.6 vs 7.0 out of 10).
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Key differences
- Price
- PlexusDx $129/mo no prepay listed; SkinnyRx $149.25/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
- Coverage
- PlexusDx 50 states (SkinnyRx doesn't publish a state list)
- Included
- PlexusDx: medication, clinician visits; SkinnyRx: medication, clinician visits, shipping
- Safety
- FDA warning letters on record: PlexusDx none, SkinnyRx 1
PlexusDx
Affiliate partnerBest for nationwide compounded GLP-1 with optional genetic-test personalization
semaglutide
$129
microdose plan
Our score 7.0/10
SkinnyRx
Affiliate partnerBest for compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
semaglutide
$149.25
“starting at” price
Our score 7.6/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
PlexusDx
SkinnyRx
Price
Semaglutide / month
$129/mo
microdose plan
$149.25/mo
“starting at” price
Semaglutide / year (modeled)
$1,548
$1,791
Tirzepatide / month
$249/mo
starting dose
$224.25/mo
“starting at” price
Tirzepatide / year (modeled)
$2,988
$2,691
Oral semaglutide / month
Not listed
$199/mo
“starting at” price
Brand Wegovy / Ozempic / month
Not listed
$1,400/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,400/mo
Coverage
State availability
50 states
List not published
Oral option listed
Not listed
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Plan quoted after intake; a price is published
Refunds
Not disclosed
90-day money-back guarantee
FDA warning letters
Better on this row: None on record
1 warning letter
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose PlexusDx if…
- Publishes its full state list (50 states)
- No FDA warning letters on record (SkinnyRx has 1)
- Optional Precision Peptide genetic panel adds a personalization angle
What to weigh up
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
Choose SkinnyRx if…
- Lists oral compounded semaglutide, brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which PlexusDx doesn't price
- Licensed US clinicians on every prescription
- Discreet shipping included; cancel anytime
What to weigh up
- 1 FDA warning letter on record
- No published state list; confirm yours at signup
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
PlexusDx
7.0/10
SkinnyRx
7.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
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Luvo Health
Compounded and brand GLP-1s, oral tablets and microdosing on one public price list
Read full review →From $209/4 wks (billed per 4 weeks)
Get started →From $99/mo (“starting at” price)
Get started →Gala
Compounded semaglutide or tirzepatide at one all-doses price on a yearly plan, with free shipping
Read full review →From $129/mo (starting dose)
Get started →PlexusDx vs SkinnyRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking, or alternatives to PlexusDx and SkinnyRx.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.