Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

Pillar Health vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Pillar Health logo

Pillar Health

7.5
★★★★☆3.8/5

Best for: flat per-dose GLP-1 pricing with no membership, and a half-price first month

Visit Pillar Health →
VS
NewSelf logo

NewSelf

8.3
★★★★☆4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf →

Pillar Health and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $189/mo, and NewSelf edges ahead overall (8.3 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Pillar Health

Monthly program, every dose 0.25 mg to 2.4 mg/weekCompounded
$189$94.5/mo
Save 50% right now
semaglutide

Code PILLAR50 cuts the first month to $94.50; $189/mo from month two, same at every dose.

Monthly program, every dose 2.5 mg to 15 mg/weekCompounded
$249$124.5/mo
Save 50% right now
tirzepatide

Code PILLAR50 cuts the first month to $124.50; $249/mo from month two, same at every dose.

Microdosing program, clinician-set dose, monthlyCompounded
$199$99.5/mo
Save 50% right now
tirzepatide

Product page lists $199/mo; the category card for the same program reads "249/month".

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

Get alerted when GLP-1 prices drop

Join the GLP-1 price-watch list — we re-verify 520+ providers' prices on their own sites and email you when tracked prices move.

What’s included

Pillar Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Pillar Health

7.5/10

Overall

NewSelf

8.3/10

Value25%

8.5A
vs
B
9.0

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

5.5A
vs
B
8.3

Accessibility10%

8.0A
vs
B
8.5

Support10%

6.0A
vs
B
7.9

Features & Coverage

FeaturePillar HealthNewSelf
Starting Price$189/mo✓$100/mo
Features✓8 features6 features
States Available4949
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted✓ Yes—
FDA Warnings✓None1 warning

About Pillar Health

Pillar Health is a Michigan-based telehealth storefront selling compounded semaglutide and tirzepatide programs at one flat monthly price that does not rise with your dose: $189/mo for semaglutide and $249/mo for tirzepatide, with no membership fee and free shipping. Prescribers come through the Architek Health provider network. A first-order code halves the first month, and prices are shown before any intake.

Read our full Pillar Health review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Pillar Health

What we like

  • One flat price at every dose: $189/mo semaglutide, $249/mo tirzepatide, and it does not climb as you titrate
  • No membership fee on top; the program price covers the clinician, dose changes and the medication
  • Prices are printed on the product pages before you answer a single health question
  • Code PILLAR50 takes 50% off the first month ($94.50 semaglutide, $124.50 tirzepatide)
  • Available in 48 states plus Washington, D.C.; only Alaska and Mississippi are excluded
  • Names its prescriber network (Architek Health) and advertises the price as locked in for life
  • A lower-cost microdosing tirzepatide program is offered alongside the standard ladder

Watch-outs

  • No compounding pharmacy is named; you are told to email support to learn which pharmacy fills your order
  • Pillar does not run its own checkout, and its refund policy defers entirely to the third-party platform you pay on
  • Billing, renewal and cancellation terms are shown only after you create an account
  • The terms of use ask customers not to disparage the company publicly, including on social media
  • The microdosing program is listed at $199/mo on its product page but "249/month" on the category page
  • A self-described early-stage company; support is email and web form only, with no phone number
  • Compounded only, and the site confirms compounded semaglutide and tirzepatide are not FDA-approved

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Pillar Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Pillar Health remains a solid alternative, especially if you're looking for flat per-dose GLP-1 pricing with no membership, and a half-price first month.

Choose Pillar Health if…

You want flat per-dose GLP-1 pricing with no membership, and a half-price first month and a starting price around $189/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

No insurance needed · vetted by our editors

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

8.3

Found

Mainstream telehealth GLP-1 access

7.4

Breeze Meds

Compounded GLP-1 access with named prescribers and 4-pharmacy network

Pillar Health vs NewSelf: FAQ

NewSelf is cheaper. Its lowest ongoing monthly cash price is $100/mo, compared with $189/mo for Pillar Health. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
NewSelf scores higher overall at 8.3/10 versus 7.5/10, and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. That said, Pillar Health is a better fit if you want flat per-dose GLP-1 pricing with no membership, and a half-price first month.
Pillar Health and NewSelf both list availability in 49 states.
Neither Pillar Health nor NewSelf is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, Pillar Health is cheaper at $94.5/mo versus $100/mo at NewSelf.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Pillar Health and NewSelf head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.