Pepti vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Pepti
Best for: the lowest all-in monthly price we have verified on compounded semaglutide, labs included
Visit Pepti →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Pepti and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Pepti starts lower at $99/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Pepti
All-in monthly subscription covering medication, physician care, labs and shipping. A one-time non-subscription vial is $124.
All-in monthly subscription. A one-time non-subscription vial is $249.
Oral semaglutide, priced above the injectable.
Oral tirzepatide, priced above the injectable.
NewSelf
All dosages same price
All dosages same price
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 440+ providers' prices on their own sites and email you when tracked prices move.
What’s included
Pepti
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Included
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Pepti
7.9/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Pepti | NewSelf |
|---|---|---|
| Starting Price | ✓$99/mo | $100/mo |
| Features | ✓7 features | 6 features |
| States Available | 36 | ✓49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
About Pepti
Pepti is a Delaware-registered telehealth platform selling doctor-prescribed compounded peptides and GLP-1s across 36 states. Injectable semaglutide is $99 a month all-in and tirzepatide $199, each covering medication, physician review, baseline labs, refill management and shipping in a single flat price that does not rise with dose. The catalogue runs to more than 120 products across weight loss, hormones and TRT, recovery, cognitive and skin categories, plus at-home bloodwork. Pepti is a platform, not a prescriber, and does not bill insurance.
Read our full Pepti review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Pepti
What we like
- At $99/mo all-in, injectable semaglutide is among the cheapest verified prices in our catalogue.
- States plainly that all doses cost one flat monthly price, so titrating up never raises the bill.
- Publishes a page for each of the 36 states it serves, and the page count matches its claim exactly.
- Names the reviewing physician, Dr. Gene Lee MD, and discloses pepti LLC as the Delaware operating entity.
Watch-outs
- The homepage shows an "FDA Cleared" badge beside peptide therapy, though product pages correctly say compounded drugs are not FDA-approved.
- Neither the 503A nor the 503B compounding pharmacy is named, so you cannot check who dispenses.
- The listed address, a Newark Delaware suite, is a shared registered-agent address rather than a clinical office.
- Cash-pay only with no insurance billing, and the oral formulations jump to $249 and $399 a month.
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Pepti with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Pepti remains a solid alternative, especially if you're looking for the lowest all-in monthly price we have verified on compounded semaglutide, labs included.
Choose Pepti if…
You want the lowest all-in monthly price we have verified on compounded semaglutide, labs included and a starting price around $99/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
MEDVi
Switching between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →Liv Body
Compounded GLP-1 paired with a muscle-preservation supplement stack
From $179/mo
Get started →DudeMeds
Men seeking no-fee GLP-1 access with oral and injectable options
From $175/mo
Get started →Pepti vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Pepti and NewSelf head-to-heads in the same category.
- Pepti vs Amazon One Medical
- Pepti vs Vytora Health
- Pepti vs CoreAge Rx
- NewSelf vs EverSlim
- NewSelf vs Found
- NewSelf vs Elara Health and Wellness
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.