Pepti vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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Pepti
Best for: the lowest all-in monthly price we have verified on compounded semaglutide, labs included
Visit Pepti →
Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →Pepti and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Pepti starts lower at $99/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Pepti
All-in monthly subscription covering medication, physician care, labs and shipping. A one-time non-subscription vial is $124.
All-in monthly subscription. A one-time non-subscription vial is $249.
Oral semaglutide, priced above the injectable.
Oral tirzepatide, priced above the injectable.
Amazon One Medical
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What’s included
Pepti
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Included
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Pepti
7.9/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Pepti | Amazon One Medical |
|---|---|---|
| Starting Price | ✓$99/mo | $149/mo |
| Features | ✓7 features | 6 features |
| States Available | 36 | ✓50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
About Pepti
Pepti is a Delaware-registered telehealth platform selling doctor-prescribed compounded peptides and GLP-1s across 36 states. Injectable semaglutide is $99 a month all-in and tirzepatide $199, each covering medication, physician review, baseline labs, refill management and shipping in a single flat price that does not rise with dose. The catalogue runs to more than 120 products across weight loss, hormones and TRT, recovery, cognitive and skin categories, plus at-home bloodwork. Pepti is a platform, not a prescriber, and does not bill insurance.
Read our full Pepti review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
Pepti
What we like
- At $99/mo all-in, injectable semaglutide is among the cheapest verified prices in our catalogue.
- States plainly that all doses cost one flat monthly price, so titrating up never raises the bill.
- Publishes a page for each of the 36 states it serves, and the page count matches its claim exactly.
- Names the reviewing physician, Dr. Gene Lee MD, and discloses pepti LLC as the Delaware operating entity.
Watch-outs
- The homepage shows an "FDA Cleared" badge beside peptide therapy, though product pages correctly say compounded drugs are not FDA-approved.
- Neither the 503A nor the 503B compounding pharmacy is named, so you cannot check who dispenses.
- The listed address, a Newark Delaware suite, is a shared registered-agent address rather than a clinical office.
- Cash-pay only with no insurance billing, and the oral formulations jump to $249 and $399 a month.
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out Pepti with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Pepti remains a solid alternative, especially if you're looking for the lowest all-in monthly price we have verified on compounded semaglutide, labs included.
Choose Pepti if…
You want the lowest all-in monthly price we have verified on compounded semaglutide, labs included and a starting price around $99/mo.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
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Get started →Pepti vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.