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NextMeds vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NextMeds logo

NextMeds

7.1
★★★3.6/5

Best for: flat-price compounded semaglutide or tirzepatide bundled with a care coach and registered dietitian

Visit NextMeds
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

NextMeds and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $129/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NextMeds

InjectableCompounded
$129/mo
semaglutide

Compounded Semaglutide Membership — flat, same price every dose; bundles telehealth visits, care coach, dietitian and shipping. An active promo ('starting at $100/mo', countdown timer) may lower the intro price.

InjectableCompounded
$179/mo
tirzepatide

Compounded Tirzepatide Membership — flat, same price every dose; bundles telehealth visits, care coach, dietitian and shipping. An active promo may lower the intro price.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

NextMeds

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NextMeds

7.1/10

Overall

NewSelf

8.3/10

Value25%

7.0A
vs
B
9.0

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

6.2A
vs
B
8.3

Accessibility10%

8.0A
vs
B
8.5

Support10%

7.5A
vs
B
7.9

Features & Coverage

FeatureNextMedsNewSelf
Starting Price$129/mo$100/mo
Features8 features6 features
States Available5049
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About NextMeds

NextMeds is a cash-pay telehealth platform offering compounded semaglutide and compounded tirzepatide on a flat monthly membership — one price bundling the medication (if prescribed), telehealth visits, a 1:1 care coach, and a licensed registered dietitian, with free shipping and no insurance. A licensed provider reviews a free online assessment (with a live video or phone consult where a state requires it) and prescribes if appropriate; medication ships from a licensed compounding pharmacy in the Next Meds network. Available in all 50 states; cancel anytime with no auto-renewal.

Read our full NextMeds review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

NextMeds

What we like

  • Flat monthly membership bundles the medication, telehealth visits, a 1:1 care coach and a licensed registered dietitian — one price, no hidden fees
  • Same price every dose, no auto-renewal, cancel anytime; free shipping and no insurance needed (FSA eligible)
  • Names a compounding pharmacy partner (Foothills Pharmacy) and states it services all 50 states
  • Free, no-obligation online assessment before you pay anything

Watch-outs

  • Shows a LegitScript 'approval' but links only a generic directory search, not a verifiable seal — we couldn't independently confirm it
  • Promo-driven pricing with a countdown timer and 'price increases' urgency; the standing membership is $129 (sema) / $179 (tirz)
  • A technology platform that coordinates care, not the medical provider; individual clinicians and a medical director aren't named on the site
  • Compounded semaglutide and tirzepatide only — no brand-name (Wegovy/Zepbound) options
  • Compounded GLP-1s are not FDA-reviewed or approved — a different evidence and regulatory tier than brand-name

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out NextMeds with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. NextMeds remains a solid alternative, especially if you're looking for flat-price compounded semaglutide or tirzepatide bundled with a care coach and registered dietitian.

Choose NextMeds if…

You want flat-price compounded semaglutide or tirzepatide bundled with a care coach and registered dietitian and a starting price around $129/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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7.6

Maximus

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8.0

Sesame Care

Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding

6.9

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Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

NextMeds vs NewSelf: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.