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NewSelf vs Trally Meds

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NewSelf logo

NewSelf

8.3
★★★★☆4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf →
VS
Trally Meds logo

Trally Meds

6.8
★★★☆☆3.4/5

Best for: people who want published GLP-1 prices with free consultations and the option to buy one month at a time

Visit Trally Meds →

NewSelf and Trally Meds are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $249/mo, and NewSelf edges ahead overall (8.3 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

Trally Meds

1-month supply, auto-refills after each provider check-inCompounded
$249/mo
semaglutide

3-month supply $672 (about $224/mo). The site prices the month as four weeks: "Only $62.25 per week".

1-month supply, auto-refills after each provider check-inCompounded
$349/mo
tirzepatide

3-month supply $942 (about $314/mo). The site prices the month as four weeks: "Only $87.25 per week".

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What’s included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Trally Meds

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NewSelf

8.3/10

Overall

Trally Meds

6.8/10

Value25%

9.0A
vs
B
6.5

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

8.0A
vs
B
6.0

Trust & Safety15%

8.3A
vs
B
5.5

Accessibility10%

8.5A
vs
B
7.0

Support10%

7.9A
vs
B
7.0

Features & Coverage

FeatureNewSelfTrally Meds
Starting Price✓$100/mo$249/mo
Features6 features✓7 features
States Available49Not disclosed
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warnings1 warning✓None

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

About Trally Meds

Trally Meds is an online telehealth service with a Memphis, Tennessee address that sells compounded semaglutide and tirzepatide, along with hair loss, erectile dysfunction and anti-aging treatment. A 1-month supply costs $249 for semaglutide or $349 for tirzepatide, and a 3-month supply costs $672 or $942. Consultations and shipping are free, and plans renew automatically after each provider check-in.

Read our full Trally Meds review →

Pros & Cons

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Trally Meds

What we like

  • Prices are public before you sign up: $249 for a month of semaglutide and $349 for tirzepatide
  • Consultations and shipping are free, with no membership fee
  • Your card is only held, not charged, until a provider writes a prescription
  • Cancel anytime in the member portal, by phone or by email, with no cancellation fee
  • A 3-month supply lowers the cost to about $224 a month for semaglutide and $314 for tirzepatide
  • Publishes a support phone line with weekday hours

Watch-outs

  • The site does not say how often the 1-month supply renews, and its weekly price math treats a month as four weeks
  • Plans renew automatically until you cancel, and a charge that has already gone through is not refunded
  • All sales are final once your medication ships
  • The dispensing pharmacy is not named, and the site calls its pharmacies "FDA approved"
  • You must create an account with name, email, phone and a password before any health questions
  • The assessment page carries generic testimonials and calls the service "Telemed"
  • There are no independent customer reviews on Trustpilot yet

Our Verdict

Winner: NewSelf

NewSelf edges out Trally Meds with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Trally Meds remains a solid alternative, especially if you're looking for people who want published GLP-1 prices with free consultations and the option to buy one month at a time.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

Choose Trally Meds if…

You want people who want published GLP-1 prices with free consultations and the option to buy one month at a time and a starting price around $249/mo.

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7.6

SkinnyRx

Mainstream telehealth GLP-1 access

7.8

Embody

Low flat-rate compounded GLP-1 pricing at every dose

8.3

Found

Mainstream telehealth GLP-1 access

NewSelf vs Trally Meds: FAQ

NewSelf is cheaper. Its lowest ongoing monthly cash price is $100/mo, compared with $249/mo for Trally Meds. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
NewSelf scores higher overall at 8.3/10 versus 6.8/10, and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. That said, Trally Meds is a better fit if you want people who want published GLP-1 prices with free consultations and the option to buy one month at a time.
NewSelf lists availability in 49 states, while Trally Meds's state list is not publicly listed.
Neither NewSelf nor Trally Meds is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, NewSelf is cheaper at $100/mo versus $249/mo at Trally Meds.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring NewSelf and Trally Meds head-to-heads in the same category.

Or see the full category ranking.

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