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NewSelf vs Science & Co

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf
VS
Science & Co logo

Science & Co

7.4
★★★3.7/5

Best for: the cheapest month-to-month compounded rate, if you accept a contact gate

Visit Science & Co

NewSelf and Science & Co are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Science & Co starts lower at $89/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

Science & Co

Once-weekly compounded injection, month-to-month plan (renews every 30 days)Compounded
$89/mo
semaglutide

Month-to-month rate from the plan table. Prepay tiers: 3-month $250 ($83/mo), 6-month $486 ($81/mo), 12-month $948 ($79/mo) — each billed in one upfront charge.

Once-weekly compounded injection, month-to-month plan (renews every 30 days)Compounded
$139/mo
tirzepatide

Month-to-month rate from the plan table. Prepay tiers: 3-month $399 ($133/mo), 6-month $774 ($129/mo), 12-month $1,500 ($125/mo) — each billed in one upfront charge.

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What’s included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Science & Co

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NewSelf

8.3/10

Overall

Science & Co

7.4/10

Value25%

9.0A
vs
B
8.5

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

8.0A
vs
B
6.5

Trust & Safety15%

8.3A
vs
B
5.5

Accessibility10%

8.5A
vs
B
7.5

Support10%

7.9A
vs
B
7.5

Features & Coverage

FeatureNewSelfScience & Co
Starting Price$100/mo$89/mo
Features6 features6 features
States Available49Not disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA Warnings1 warningNone

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

About Science & Co

Science & Co is a cash-pay telehealth service selling compounded semaglutide from $89/mo and compounded tirzepatide from $139/mo month-to-month, flat at every dose, with free overnight shipping and no membership fee. Those are among the lowest month-to-month GLP-1 rates we track, but the marketing site quotes only '$2 a day' and a 12-month rate buried in a collapsed FAQ; the plan table with the real month-to-month price appears only after you hand over your name, email, phone and state.

Read our full Science & Co review →

Pros & Cons

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Science & Co

What we like

  • $89/mo month-to-month for compounded semaglutide is at the bottom of the range we track
  • Flat at every dose — 'You pay the same whether you are on your starting dose or your highest one'
  • Free overnight shipping, no membership fee and no consultation fee
  • Prepay tiers are cheaper per month and are shown side by side with the monthly rate, not instead of it
  • Published phone line and email, both staffed as 24/7 messaging with the care team
  • HSA and FSA eligible
  • Cancel any time before the next renewal from the patient portal

Watch-outs

  • The marketing site quotes only a per-day figure and the 12-month rate; the plan table appears only after you give your name, email, phone and state
  • Trustpilot has removed this company's profile as against its guidelines, while the site advertises '4.8 · 1,200+ member reviews'
  • The LegitScript badge is a self-hosted image on the company's own CDN, not a LegitScript-served seal, and its lookup shows no record
  • The monthly plan 'renews every 30 days' — 13 charges in a year, not 12
  • The advertised '$79 a month' is the 12-month tier: a single $948 charge up front
  • The compounding pharmacy is never named; the company states it is 'not a 503A or 503B compounding facility'
  • Marketing consent to email and text arrives pre-checked on the contact step
  • Named before/after testimonials repeat across pages, and the '15% lost on average' figure is labeled illustrative

Our Verdict

Winner: NewSelf

NewSelf edges out Science & Co with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Science & Co remains a solid alternative, especially if you're looking for the cheapest month-to-month compounded rate, if you accept a contact gate.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

Choose Science & Co if…

You want the cheapest month-to-month compounded rate, if you accept a contact gate and a starting price around $89/mo.

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7.3

Sunlight

Compounded GLP-1 with unlimited telehealth visits and free shipping

7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

8.3

Found

Mainstream telehealth GLP-1 access

NewSelf vs Science & Co: FAQ

Science & Co is cheaper. Its lowest ongoing monthly cash price is $89/mo, compared with $100/mo for NewSelf. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
NewSelf scores higher overall at 8.3/10 versus 7.4/10, and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. That said, Science & Co is a better fit if you want the cheapest month-to-month compounded rate, if you accept a contact gate.
NewSelf lists availability in 49 states, while Science & Co's state list is not publicly listed.
Neither NewSelf nor Science & Co is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, Science & Co is cheaper at $89/mo versus $100/mo at NewSelf.

Key terms, explained

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Continue exploring NewSelf and Science & Co head-to-heads in the same category.

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