NewSelf vs PCOS Sisters
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →PCOS Sisters
Best for: women with pcos seeking glp-1 weight and metabolic care
Visit PCOS Sisters →NewSelf and PCOS Sisters are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $150/mo, and NewSelf edges ahead overall (8.3 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
PCOS Sisters
GLP-1 management fee, membership required; billed monthly
Same 150/mo GLP-1 management fee; tirzepatide referenced in program
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
PCOS Sisters
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
PCOS Sisters
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | PCOS Sisters |
|---|---|---|
| Starting Price | ✓$100/mo | $150/mo |
| Features | 6 features | 6 features |
| States Available | ✓49 | 12 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About PCOS Sisters
PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required. Providers prescribe semaglutide (the active ingredient in Wegovy and Ozempic), tirzepatide, and oral GLP-1 options, integrated with a PCOS-focused metabolic program and fitness app. Care is available across 12 states and prescriptions are filled through named partner pharmacies including Strive Pharmacy and Striker Pharmacy. Cash-pay model, no insurance.
Read our full PCOS Sisters review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
PCOS Sisters
What we like
- Dedicated PCOS specialty model with metabolic program and fitness app included
- Transparent 150 dollars per month GLP-1 management fee
- Names real partner pharmacies (Strive, Striker) and lists phone support
Watch-outs
- Only 12 states served
- Membership required on top of the medical program
- Unclear whether pharmacy dispensing fees are separate from the 150/mo fee
Our Verdict
NewSelf edges out PCOS Sisters with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. PCOS Sisters remains a solid alternative, especially if you're looking for women with pcos seeking glp-1 weight and metabolic care.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose PCOS Sisters if…
You want women with pcos seeking glp-1 weight and metabolic care and a starting price around $150/mo.
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Direct Meds
Listed for transparent disclosure — see FDA warning and BBB complaint pattern before considering
From $249/mo
Get started →Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →NewSelf vs PCOS Sisters: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.