PCOS Sisters Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.2/10
Best for: women with pcos seeking glp-1 weight and metabolic care
PCOS Sisters is a solid telehealth option with balanced features and pricing.
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
No insurance needed · Vetted by our editors
PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required. Providers prescribe semaglutide (the active ingredient in Wegovy and Ozempic), tirzepatide, and oral GLP-1 options, integrated with a PCOS-focused metabolic program and fitness app. Care is available across 12 states and prescriptions are filled through named partner pharmacies including Strive Pharmacy and Striker Pharmacy. Cash-pay model, no insurance.
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PCOS Sisters at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $150/mo (GLP-1 management fee, membership required; billed monthly)
- Pricing model
- Flat — dose increases don't raise the monthly price
- What's included
- Medication · Consult · Shipping
- Availability
- 12 states
- FDA status
- No FDA warning letter on record
How we scored PCOS Sisters
Each dimension is scored algorithmically from PCOS Sisters’s real pricing, drugs offered, verification status, and disclosed inclusions — using the same six-dimension framework we apply to every provider.
Value25%
8.0/10At $150/mo, PCOS Sisters runs about 12% below the $170 median for GLP-1 providers. Pricing is flat across doses, so there is no escalation markup as you titrate up.
Effectiveness25%
7.7/10PCOS Sisters offers both semaglutide and tirzepatide — the two GLP-1 molecules with the strongest published weight-loss trial outcomes. An oral/needle-free option is offered for patients who avoid injections.
User Experience15%
6.9/10Online intake and platform experience — consult included in the price; 6 platform features disclosed.
Trust & Safety15%
7.6/10Key details fully confirmed by our editors; no FDA warning letters on file (last checked 2026-07-16).
Accessibility10%
6.0/10PCOS Sisters is available in 12 states — confirm yours is covered.
Support10%
5.4/10PCOS Sisters provides standard clinician follow-up; no extended coaching or community program is disclosed.
Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →
How we verified this PCOS Sisters review
Last checked July 2026- Confirmed current pricing across 2 dose/plan tiers
- Confirmed availability in 12 states
- Confirmed what the monthly price does and doesn't include
- Checked the FDA warning-letter database for enforcement actions
- Walked the public intake/checkout flow on the provider's site
Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records — see the sources below. Editorial confidence in this data: high.
GLP-1 medications PCOS Sisters offers
Tap any medication to read our plain-English guide — how it works, dosing, side effects, and what the trials found.
Pricing
Prices re-verified
GLP-1 management fee, membership required; billed monthly
Same 150/mo GLP-1 management fee; tirzepatide referenced in program
Ready to get started?
Plans and promotions change often — check PCOS Sisters's current pricing and active discounts before you decide.
What we like
- Dedicated PCOS specialty model with metabolic program and fitness app included
- Transparent 150 dollars per month GLP-1 management fee
- Names real partner pharmacies (Strive, Striker) and lists phone support
Watch-outs
- Only 12 states served
- Membership required on top of the medical program
- Unclear whether pharmacy dispensing fees are separate from the 150/mo fee
Is PCOS Sisters worth it? Our verdict
PCOS Sisters positions itself around one thing: women with pcos seeking glp-1 weight and metabolic care. It runs $150/month, flat across every dose — toward the affordable end of the market. Its standout is a needle-free oral option, which very few providers offer.
What gives PCOS Sisters its own flavor: PCOS-focused.
How much PCOS Sisters actually costs
- Compounded semaglutide — $150/month
- Compounded tirzepatide — $150/month
That puts PCOS Sisters below the roughly $170 median ongoing price across the GLP-1 providers we track — a real cost advantage.
For a direct comparison, SkinnyRx runs semaglutide and tirzepatide from $149.25/month — worth pricing against PCOS Sisters before you commit.
Medications: what PCOS Sisters prescribes
PCOS Sisters prescribes semaglutide (the active drug in Wegovy and Ozempic) and tirzepatide (the active drug in Zepbound and Mounjaro) — the two molecules with the strongest published weight-loss trial outcomes. Rather than brand-name pens, you get a compounded formulation from a licensed pharmacy — the reason the monthly cost is lower. Just know compounded drugs aren't FDA-approved as finished products, the standard caveat in this market.
PCOS Sisters's needle-free oral option is a real draw if you've been avoiding a GLP-1 because of injections. Just set expectations on the science: oral and buccal delivery of these peptides is far less studied than the injectable versions the trials used, so treat it as a convenience option rather than a proven equal to the shot.
Who PCOS Sisters is best for — and who should skip it
A good fit if you…
- are focused on the lowest ongoing monthly cost.
- are needle-averse and want a non-injectable option.
Look elsewhere if you…
- specifically want an FDA-approved brand-name pen.
- need to bill insurance — like most of this market, it's cash-pay.
Trust, safety, and medical oversight
PCOS Sisters is available in 12 states. We found no FDA warning letters on file for the provider. As with any compounded program, the most important step you can take is confirming which licensed pharmacy fills your prescription and what's in the formulation — we explain how in our scoring methodology.
Bottom line
PCOS Sisters earns its place on the shortlist mainly on price: at $150/month it's one of the more affordable ways to stay on a GLP-1, without obvious corners cut on access or oversight.
The Bottom Line
PCOS Sisters is a solid telehealth option with balanced features and pricing.
Ready to start with PCOS Sisters?
Starting at $150/month. See current pricing and start your free consultation.
PCOS Sisters might not be your best fit if…
We rank editorially, so here’s where a different provider we track may serve you better.
- If you want brand-name Ozempic, Wegovy, Mounjaro or Zepbound, consider GobyMeds.
- If the lowest possible monthly price is your top priority, consider Sesame Care (from $59/mo).
- If you want built-in coaching and behavior-change support, consider MEDVi.
Frequently Asked Questions
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
The primary regulatory filings and peer-reviewed studies cited throughout this PCOS Sisters review:
Sources & methodology — as of July 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See PCOS Sisters's current pricing
Plans start at $150/month. Start your free consultation to check eligibility and today's price.