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MyStart Health vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
MyStart Health logo

MyStart Health

7.1
★★★3.6/5

Best for: fastest compounded GLP-1 onboarding with a price lock

Visit MyStart Health
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

MyStart Health and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $299/mo, and MyStart Health is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

MyStart Health

All-inclusive (flat, price-locked across dose escalations)Compounded
$299/mo
semaglutide

Homepage FAQ verbatim: program 'starts at $299/month, excluding any discounts,' all-inclusive (consults, unlimited clinician access, meds, labs, shipping). Promo banner '$150 Off + Lifetime 25% Off' (coupon SELFLOVE25 in funnel URL) but no final promo dollar price published pre-quiz — plan-selection pricing is gated behind a signed medical attestation, so not published.

All-inclusive (flat, price-locked across dose escalations)Compounded
$299/mo
tirzepatide

Same flat $299 all-inclusive program price; tirzepatide offering confirmed via funnel testimonial ('Tirzepatide through MyStart') and FAQ injection instructions ('How to inject compounded tirzepatide'). No oral tirzepatide marketing found on the current site (stored con appears stale). Per-drug tier pricing quiz-gated = not published.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

MyStart Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Included

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

MyStart Health

7.1/10

Overall

NewSelf

8.3/10

Value25%

6.0A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.3

Accessibility10%

6.5A
vs
B
8.5

Support10%

7.9A
vs
B
7.9

Features & Coverage

FeatureMyStart HealthNewSelf
Starting Price$299/mo$100/mo
Features6 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About MyStart Health

MyStart Health offers all-inclusive compounded semaglutide and tirzepatide at $299/month with a price-lock guarantee, same-day physician consultations, and 24/7 care team access. LegitScript certified; Delaware MSO partnering with licensed US clinicians. Best-for: speed of onboarding.

Read our full MyStart Health review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

MyStart Health

What we like

  • Price Lock Guarantee — your $299 base rate doesn't rise as your dose escalates
  • Fast onboarding: roughly 5-minute intake, 24-hour prescription turnaround, 2–4 day shipping
  • 24/7 care team access with unlimited clinician messaging included
  • LegitScript certified
  • Clear Section 503A compounding disclosure on every landing page

Watch-outs

  • Not BBB accredited — C+ rating with 10 complaints, mostly shipping delays and support access
  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
  • Markets oral tirzepatide, but no FDA-approved oral tirzepatide exists
  • Very new company (incorporated May 2024) with a limited track record
  • Pharmacy partners not named, so 503A compliance can't be independently verified
  • Efficacy claims rest on a homepage survey of just 16 self-reporting customers

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: MyStart Health

MyStart Health is our recommended choice here, particularly for fastest compounded GLP-1 onboarding with a price lock. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose MyStart Health if…

You want fastest compounded GLP-1 onboarding with a price lock and a starting price around $299/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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MyStart Health vs NewSelf: FAQ

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