MyStart Health vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
MyStart Health
Best for: fastest compounded GLP-1 onboarding with a price lock
Visit MyStart Health →
Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →MyStart Health and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $299/mo, and MyStart Health is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
MyStart Health
Homepage FAQ verbatim: program 'starts at $299/month, excluding any discounts,' all-inclusive (consults, unlimited clinician access, meds, labs, shipping). Promo banner '$150 Off + Lifetime 25% Off' (coupon SELFLOVE25 in funnel URL) but no final promo dollar price published pre-quiz — plan-selection pricing is gated behind a signed medical attestation, so not published.
Same flat $299 all-inclusive program price; tirzepatide offering confirmed via funnel testimonial ('Tirzepatide through MyStart') and FAQ injection instructions ('How to inject compounded tirzepatide'). No oral tirzepatide marketing found on the current site (stored con appears stale). Per-drug tier pricing quiz-gated = not published.
Amazon One Medical
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 390+ providers' prices on their own sites and email you when tracked prices move.
What’s included
MyStart Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Included
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MyStart Health
7.1/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | MyStart Health | Amazon One Medical |
|---|---|---|
| Starting Price | $299/mo | ✓$149/mo |
| Features | 6 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About MyStart Health
MyStart Health offers all-inclusive compounded semaglutide and tirzepatide at $299/month with a price-lock guarantee, same-day physician consultations, and 24/7 care team access. LegitScript certified; Delaware MSO partnering with licensed US clinicians. Best-for: speed of onboarding.
Read our full MyStart Health review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
MyStart Health
What we like
- Price Lock Guarantee — your $299 base rate doesn't rise as your dose escalates
- Fast onboarding: roughly 5-minute intake, 24-hour prescription turnaround, 2–4 day shipping
- 24/7 care team access with unlimited clinician messaging included
- LegitScript certified
- Clear Section 503A compounding disclosure on every landing page
Watch-outs
- Not BBB accredited — C+ rating with 10 complaints, mostly shipping delays and support access
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Markets oral tirzepatide, but no FDA-approved oral tirzepatide exists
- Very new company (incorporated May 2024) with a limited track record
- Pharmacy partners not named, so 503A compliance can't be independently verified
- Efficacy claims rest on a homepage survey of just 16 self-reporting customers
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
MyStart Health is our recommended choice here, particularly for fastest compounded GLP-1 onboarding with a price lock. Amazon One Medical is a solid alternative, especially if you want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings — compare the six-dimension breakdown and pricing below to weigh them for your situation.
Choose MyStart Health if…
You want fastest compounded GLP-1 onboarding with a price lock and a starting price around $299/mo.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Yucca Health
Mainstream telehealth GLP-1 access
From $146/mo
Get started →TrimRx
Best overall value
From $135/mo
Get started →Sprout Health
LegitScript-verified compounded GLP-1 via named pharmacies
From $149/mo
Get started →MyStart Health vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring MyStart Health and Amazon One Medical head-to-heads in the same category.
- MyStart Health vs Vytora Health
- MyStart Health vs CoreAge Rx
- MyStart Health vs EverSlim
- Amazon One Medical vs Found
- Amazon One Medical vs NewSelf
- Amazon One Medical vs Elara Health and Wellness
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.